Lesson 3 Flashcards
When did Paul Ehrlich worked on developing a synthetic chemical effective against infectious causing cells
1920s
Year when sulfonamides was introduced
1935
Who discovered penicillin
Alexander Fleming
When was penicillin introduced
1928
What do you call the medicine given to bacteria?
Anti-biotic
To kill the cell
Bactericidal
To prevent reproduction of the cell
Bacteriostaric
They vary in their effectiveness against invading organism
Anti-infectives
Useful in treating a wide variety of infections
Broad spectrum of activity
Effective against only a few microorganisms with a very specific metabolic pathway
Narrow spectrum of activity
What spectrum: azithromycin, amoxicillin, tetracycline
Broad spectrum of activity
What spectrum: older penicillin g
Narrow spectrum of activity
What is the goal of anti-infective therapy
To reduce the population of the invading organism
Immune response is a ________ process
Complex
Anti-infectives act on a specific enzyme or biological process
Resistance
Microorganisms that were once sensitive to the particular drug have begun to develop acquired resistance
Acquired resistance
How to prevent resistance
Complete the prescribed dose of anti biotics always
This can be examined by ova and parasites
Stool by fecalysis
How to identify pathogen
Done by culture
Fecalysis
Factors affecting prescribing anti-infective agents
Identification of the correct pathogen
Selection of the right drug
It is the drug to drug interaction
Combination therapy
How many ml of sterile water; how about the said medication?
0.9 ml ; 0.1 ml
ADVERSE REACTIONS TO ANTI-INFECTIVE THERAPY
Kidney damage
Gastrointestinal tract toxicity
Neurotoxicity
Hypersensitivity reaction
Superinfections
Chemicals that inhibit bacteria
Antibiotics
