Lesson 14

Question 1

Act as the same site as the neurotransmitter acetylcholine

Answer 1

Cholinergic agonist

Question 2

Increase the activity of ACH (acetylcholine)

Answer 2

Cholinergic agonist

Question 3

These receptor sites are found throughout the body, so their stimulation produces similar effects when the parasympathetic nervous system is activated

Answer 3

Parasympathomimetics

Question 4

Give examples of indirect-acting cholinergic agonists

Answer 4

Alzheimers Disease
Myasthenia Gravis

Question 5

Similar to ach and react directly with receptor sites to cause the same reaction

Answer 5

Direct-acting Cholinergic Agents

Question 6

Common examples of Direct-acting Cholinergic Agonist

Answer 6

Bethanechol and pilocarpine

Question 7

Used as agents to increase bladder tone, urinary excretion, and GI secretions

Answer 7

Direct-acting Cholinergic Agonist

Question 8

Used to treat non-obstructive postoperative and pospartum urinary retention to treat neurogenic bladder atony

Answer 8

Bethanechol

Question 9

An opthalmic agent use to induce miosis or pupil constriction

Answer 9

Carbachol

Question 10

Betanechol is approved for treatment of neurogenic bladder in children _____

Answer 10

Older than 8 years of age

Question 11

Bind to muscarinic receptors and used to increase secretion in the mouth and gI tract and relieve symptoms of dry mouth

Answer 11

Cevimeline and pilocarpine

Question 12

Used to control myasthenia gravis and for reversal of neuromuscular junction

Answer 12

Neostigmine
Pyridostigmine

Question 13

Used for diagnosis of myasthenia gravis

Answer 13

Edrophonium

Question 14

Do not react directly with ACH receptor sites

Answer 14

Indirect-acting cholinergic agonist

Question 15

They react chemically chemically with acetylcholinesterase

Answer 15

Non-directing cholinergic agonist

Question 16

Enzyme breaking down acetylcholine

Answer 16

Acetylcholinesterase

Question 17

The ones bind irreversibly are not used therapeutically, they are being developed as

Answer 17

Nerve gas to be used as weapons

Question 18

The antidote for indirect-acting cholinergic agonist

Answer 18

Pralidoxime

Question 19

Two main categories of Non-directing cholinergic agonist

Answer 19

Agents used to treat myasthenia gravis
Agents used to treat alzheimers disease

Question 20

React with the enzyme acetylcholinesterase

Answer 20

Non-directing cholinergic agonist

Question 21

These agents increase the levels of acetylcholine

Answer 21

Agents for myasthenia gravis

Question 22

This agent cause elevated ACH levels in the cortex

Answer 22

Agents for Alzheimers disease

Question 23

Non-directing cholinergic agonist should be orally administered by?

Answer 23

Empty stomach

Question 24

Drugs that oppose the affects of acetylcholine

Answer 24

Anticholinergics

Question 25

They lyse and block the effects of parasympathetic nervous system

Answer 25

Parasymphatolytics

Question 26

Currently the only widely used anticholinergic drugs

Answer 26

Atropine

Question 27

It used to decrease GI activity and secretions

Answer 27

Anticholinergics

Question 28

Basically erosions in the lining of GIT caused by increased HCL production

Answer 28

GI ulcer

Question 29

GI ulcer is commonly caused by

Answer 29

H. Pylori infection

Question 30

Competitively blocking thE ACH receptors

Answer 30

Anticholinergics

Question 31

Atropine, a protoype drug, derived from the plant ______

Answer 31

Belladonna

Question 32

Used to depress salivation and bronchial secretions and to dilate the bronchi

Answer 32

Atropine

Question 33

Work by blocking only muscarinic effe ctors in the parasympathetic nervous system

Answer 33

Atropine Scopolamine