Lesson 19 Flashcards
The bad cholesterol
Ldl / Low Density Lipoprotein
The good cholesterol
HDL / High Density Lipoprotein
It absorbs cholesterol in the blood and carries it back to the liver
HDL
High levels of _______ can lower the risk of heart disease and stroke
HDL
High levels of _______ rises the risk of heart disease and stroke
LDL
Type of fat in your blood that your body uses for energy
Triglycerides
Elevated/increased level of lipid(fats) in the blood
Hyperlipidemia
How to prevent hyperlipidemia
Healthy diet
Limit alcohol
Physical activity
Smoking cessation
Use of medication
Lower serum levels of cholesterol and various lipids
Antihyperlipidemic drugs
Also known as lipid lowering agents
Anti-hyperlipidemic drugs
Example of cardiovascular diseases
Heart attack
Stroke
What is abnormal lipid levels
Dyslipidemia
Plaques is also called as
Atheromas
The leading cause of death worldwide, and its incidence is high in people with hyperlipidemia
CAD / Coronary Artery Disease
Drugs that lower serum LDL levels
Bile Acid Sequestrants
HMG-CoA Reductase Inhibitor
Cholesterol Absorption Inhibitor
Reduce LDL by binding acids in the digestive tract
Bile Acid Sequestrants
Used to normalise high serum level of cholesterol
Bile Acid Sequestrants
High cholesterol and high LDL
Hypercholesterolemia
Used to treat hypercholesterolemia
Bile Acid Sequestrants
Used to treat pruritus associated with partial biliary obstruction
Cholestyramine
Prevent bile from being secreted into the intestines
Bile obstruction
The suffix of HMG-CoA Reductase Inhibitors
Statin
Inhibits the enzyme HMG-COA reductase
HMG-CoA Reductase Inhibitors
Involved in the production of cholesterol in liver
HMG-CoA Reductase
Block the cholesterol synthesis in the body
HMG-CoA Reductase Inhibitors
Give drugs of HMG-CoA Reductase Inhibitors
Pravastatin
Lovastatin
Simvastatin
Atorvastatin
Used as prophylaxis myocardial infarction
Atorvastatin
Breaking down of muscles that may lead to disability
Rhabdomyolysis
One of the new class approved in 2003 to lower cholesterol levels
Cholesterol Absorption Inhibitors
What is the target of Cholesterol Absorption Inhibitors
Small intestine
Lower the cholesterol levels by reducing the absorption of dietary cholesterol from the intestines
Cholesterol Absorption Inhibitors
Block the absorption of dietary cholesterol
Cholesterol Absorption Inhibitors
Drugs of Cholesterol Absorption Inhibitors
Ezetimibe
Time peak for cholesterol synthesis
Midnight to 5 am