Lesson 1 Flashcards

Diagnostic tests

1
Q

CSF analysis contraindications

A

↑ICP
clotting problems
Chiari-like malformation
AA instability or trauma

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2
Q

Serology for infectious dz dogs

A

Neospora
Toxoplasma
CDV
Cryptococcus
Tick borne dz

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3
Q

Serology for infectious dz cats

A

FIV
FeLV
FIP
Toxoplasma
Cryptococcus

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4
Q

Myelography

A

IVDD
Guide surgery (which site and disc)
Neuro complications

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5
Q

Computed tomography

A

Trauma
Acute IVDD in chondrodystrophic
Spinal stabilisation

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6
Q

Immune mediated dz

A

Acetylcholine receptor antibodies titres
gold standard diagnostic tool for acquired Myasthenia Gravis
Type IIM antibodies titres gold standard for Masticatory Muscle Myositis

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7
Q

Electromyography

A

records spontaneous muscle electrical activity
normal muscle at rest is electrically silent
destabilization of the muscle cell membrane results is spontaneous discharge
ID denervated/ damaged muscles

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8
Q

Nerve conduction velocities

A

Evaluates peripheral nerve function
Calculated by stimulating nerve at least at 2
different points
Amplitude - Axons
Velocity - Myelin

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9
Q

Repetitive nerve stimulation

A

Evaluates n-m junction
Series of 10 repetitions of stimulus
Myasthenia gravis

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10
Q

Electroencephalography

A

Records spontaneous electrical activity in cerebral cortex
5-12 electrodes in head
Seizures / brain death

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11
Q

Paroxysmal Dyskinesia
(movement disorder)

A

Recurrent involuntary movement without consciousness changing
Basal nuclei signalling abnormality
Idiopathic and genetic (CKCS)

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12
Q

Other non seizures

A

Idiopathic head tremor (boxer)
Episodic muscle stiffness
Narcolepsy
Vestibular episodes

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13
Q

Seizure = forebrain
Other forebrain signs

A

Contralateral proprioception deficits
Head turn/ circling towards lesion

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14
Q

Seizure causes

A

Reactive - metabolic/ toxic
Idiopathic - no interictal neuro abnormalities (normal neuro outside of post ictal)
Structural - cerebral pathology (inflammation, neoplasm, trauma)

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15
Q

Progression of deficits

A

Improve- vascular, trauma, toxin
Worsen- inflammation, metabolic (can be both), degenerative, neoplasm

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16
Q

Lateralisation of deficit

A

Asymmetrical - Vascular, inflammation, trauma, metabolic, neoplasia
Symmetrical- Metabolic, toxin, hypoxia, degenerative

17
Q

Initial neuro assessment

A

Hx - description of episodes, non ictal changes
Exam - abn asym - structural lesion
abn sym - metabolic/
bilateral lesion
Bloods - extra cranial causes (bile
acid stim test
MRI/ CSF - if asym deficits

18
Q

Seizure tx

A

MOA - inhibition by facilitating GABA
Less excitatory transmission
Modulate cell membrane conductance
Phenobarbitone (GABA MOA)
Bromide (Cell mem) (NOT FOR CATS)
Imepitoin (GABA MOA)

19
Q

Emergency seizure management

A

Diazepam - IV
Phenobarbitone - IV (20min)
Ket
Propofol - abolish seizure signs

20
Q

Neuro grades

A

1 - pain (norm neck), no deficits
2 - ataxic paretic
3 - support needed for ambulation
4 - paralysis
5 - loss of pain perception

21
Q

Vertebral location

A

C1-5: norm to high TL and PL reflexes
C6-T2: less TL/ norm to high PL
T3-L3: norm TL/ norm to high PL
L4-S3: norm TL/ less PL

22
Q

Per acute presentations

A

Vascular - FCE (dog), Stroke (cats),
Trauma - Acute non compressive annulus pulposus extrusion
Supportive care and physio, no Sx

23
Q

Ischaemic myelopathies

A

SC blood supply interrupted
Per acute, not painful
Lateralised
Dogs - FibroCartilagenous Embolism

24
Q

ANNPE

A

Acute non compressive annulus pulposus extrusion
Trauma
Acute, not pain/ progressive
Cord contusion with minimal compression

25
Q

Fracture and luxations

A

Trauma
Neuro exam
Thorax, abd radiograph (orthoganol)

26
Q

Fr continued compartment model

A

Dorsal - articular processes, spinous process, support tissue
Mid - dorsal longitudinal ligament, dr annulus fibrosus
Ventral - rest of vertebral body

27
Q

Fr tx

A

Stabilise and analgesia
Sx / splint
Decompression
PTS if no deep pain perception

28
Q

Acute -IVDD most common (t1)

A

Chondrodystrophic - 1/2yo, chondroid metamorphosis, IVD dehydrates and hayline cartilage invasion
Non chondro breeds - mid age, fibroid metamorphosis, fibrocartilage invasion

29
Q

IVDD types

A

1 - Herniation of nucleus pulposus through annular fibres (extrusion)
2 - annular protrusion (old non chondro breeds) (protrusion)

30
Q

IVDD tx

A

Conservative -
Strict rest 1m, analgesia
Sx -
Grade >3, severe pain, no rest improvement

31
Q

Steroid responsive meningitis

A

Neck pain in young dogs
CS - lethargy, cervical rigidity, concurrent IMPA
Dx - CSF analysis
Tx - Corticosteroids (ciclosporin)

32
Q

Discospondylitis

A

IVD infection and adjacent vertebrae (L7-S1)
CS - spinal pain
Dx - radiograph (narrow IVD space)
Tx - Ab 2m, Analgesia

33
Q

MUO (Meningomyelitis of unknown origin)

A

Acute, multifocal and progressive
Dx - MRI, CSF (mononuclear)
Tx - corticosteroids

34
Q

Spinal neoplasia

A

Chronic, progressive, pain
Extradural - primary vert., lymphoma
Intradural extramedullary - meningioma, nephroblastoma, nerve sheath
Intradural Intramedullary - glioma,
Tx - decompress, radiation, palliative

35
Q

Cervical spondylomyelopathy (wobblers)

A

Rottweiler
Cs - short stilted gait and TL muscle atrophy
Multifactorial cause
Tx - conservative/ sx

36
Q

Lumbosacral degenerative stenosis

A

CS - exercise intolerance, lameness, lumbosacral pain, incontinence
Dx - multifactorial
Tx- conservative/ Sx

37
Q
A