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Kindergeneeskunde > Les 20 - Hematologie > Flashcards

Les 20 - Hematologie Flashcards

1
Q

kenmerken anemie door parvoB19

A 
koorts
exntheem
Hb laag
reticulocyten laag
bili nl
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2
Q

gevolg parvoB19 bij onderliggende aandoening

A

RBC aplasie

transiente erythroblastopenie

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3
Q

kenmerken ferriprieve anemie

A

reticulocyten nl/laag
bili nl
MCV laag

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4
Q

oorzaken ferriprieve anemie

A

bloeverlies GI
lage Fe voorraad
laag ferritine

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5
Q

behandeling ferriprieve anemie

A

dieet +Fe supplementen

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6
Q

kenmerken congenitale sferocytose

A 
gestegen reticulocyten
gestegen bili
asympt splenomegalie
anemie
icterus
galstenen
aplastische crisis
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7
Q

behandeling congenitale sferocytose

A

splenectomie + vaccinaties + AB profylaxe

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8
Q

kenmerken G6PD deficientie

A

gestegen reticulocyten
gestegen bili
icterus, donkere urine door favabonen, bepaalde GM, infecties

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9
Q

behandeling G6PD deficientie

A

uitlokkende factoren vermijden

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10
Q

kenmerken thalassemie

A 
reticulocyten nl/gestegen
bili gestegen 
MCV gedaald
icterus
transfusienood
hepatosplenomegalie
groeivertraging
botovergroei
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11
Q

behandeling thalassemie

A

hypertransfusie + Fe chelatie
stamcelTx
gentherapie

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12
Q

kenmerken sikkelcelanemie

A 
reticulocyten normaal
bili gestegen 
herhaalde icterische crisissen
vaso-occlusieve crisissen
pijn
frequente infecties + nood opname
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13
Q

diagnose sikkelcelanemie

A

gestegen bili

eiwitelektroforese: gestegen HbF

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14
Q

behandeling sikkelcelanemie

A 
pijnstilling
hydratatie
behandel bijkomende infecties
transfusie
hydrea
transplantatie
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15
Q

leeftijd optreden hemofilie

A

neonataal/kleuter

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16
Q

leeftijd optreden vWD

A

adolescent

17
Q

kenmerken hemofilie

A

bloedingen in spieren en gewrichten
neuropathien
hemartrose

18
Q

behandeling hemofilie

A

goed opvolgen
factor toedienen
vermijden NSAIDs, aspirine
GEEN IM inspuitingen!!!

19
Q

kenmerken vWD

A

mucosale bloedingen
ecchymosen
verlengd bloeden na tandextractie, HK, bevalling, menorragie

20
Q

behadeling vWD

A

desmopressine

vWF concentraat

21
Q

kenmerken ITP

A 
petechien
purpura
neusbloedingen
geisoleerde thrombopenie
na virale infectie
22
Q

behandeling ITP

A

hoge dosis IV Ig
steroiden (pas na BM onderzoek)
BP transfusie

23
Q

complicatie ITP

A

evolutie naar chronische ITP (20%)

24
Q

behandeling chronische ITP

A

rituximab
TPO analogen
splenectomie

25
Q

kinderen met trombose/leukemie screenen op

A

C/S deficientie

factor V Leiden

26
Q

kenmerken auto-immune neutropenie

A

= banale neutropenie
minder goed genezende navel
banale infecties
otitis media

gaat spontaan weg na 2j

27
Q

diagnose auto-immune neutropenie

A

auto-As opsporen in bloed

28
Q

behandeling auto-immune neutropenie

A

geruststellen

29
Q

kenmerken ernstige congenitale neutropenie

A

vanaf de geboorte veel verschillende ontstekingen

Kindergeneeskunde (21 decks)

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