Les 19 - Maligniteiten bij kinderen Flashcards

1
Q

Top 3 pediatrische kankers in Belgie

A

leukemie
lymfoom
CZS

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2
Q

symptomen leukemie

A
nachtelijke botpijn
vermoeidheid
anemische symptomen
algemene malaise
vergrote klieren
hepatosplenomegalie
petechien
bloedneuzen
braken
hoofdpijn
vergrote testes
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3
Q

diagnose leukemie

A
PB: blasten, laag Hb
BM aspiraat, botbiopsie
LP
stolling
RX
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4
Q

kenmerken lymfomen

A

gezwollen, pijnloze klieren
lokale druk
soms B-symptomen
bij adolescenten

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5
Q

diagnose lymfoma

A
excisiebiopsie
beenmergbiopt
LP
radiologie
FBC+biochemie
PET-CT
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6
Q

behandeling lymfoma

A

hodgkin: chemo-radio

non-hodgkin: chemo

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7
Q

kenmerken CZS tumor

A
hoofdpijn
nausea en braken
veranderd humeur
focale convulsies
lethargisch
visusstoornissen

(jong kind: macrocefalie/bulging fontanel)

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8
Q

diagnose CZS tumor

A

biopsie
LP
MRI -> localisatie

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9
Q

kenmerken supratentorieel/ corticaal CZS tumor

A

convulsies
hemiplegie
focale neurologische tekenen

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10
Q

kenmerken cerebellair en IVe ventrikel CZS tumor

A

subtiele afwijkende gangstoornissen

discoordinatie bij oogbewegingen

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11
Q

kenmerken midline CZS tumor

A

bitemporale hemianopsie

polydipsie

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12
Q

kenmerken hersenstam tumor

A

piramidale tract tekenen

craniale zenuw uitval

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13
Q

behandeling CZS tumor

A
neurochirurgie
VP drain
debulking excisie
chemo
radio
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14
Q

kenmerken neuroblastoom

A
abdominale massa met druk (!!! geen pijn!!!)
hypertensie
algemene malaise
hepatomegalie
bleek
botpijn --> mankend kind
orthopatische symptomen
Racoon eyes
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15
Q

diagnose neuroblastoom

A
urinaire catecholamines
tumormerkers in bloed
MRI
BM
MIBG-scan
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16
Q

behandeling neuroblastoom

A

chemo
radio
chirurgie
autologe stamcelTx

17
Q

kenmerken Wilms tumor = nefroblastooom

A

hematurie
abdominale massa (+ pijn)
hypertensie

18
Q

diagnose nefroblastoom

A

echo

19
Q

behandeling nefroblastoom

A

chemo + HK

adjuvante therapie!!

20
Q

kenmerken bottumoren

A

meer bij adolescenten

nachtelijk botpijn lange botten

21
Q

diagnose bottumoren

A

RX

MRI

22
Q

behandeling bottumoren

A

neoadj chemo + HK

RT

23
Q

kenmerken retinoblastoom

A

jonge kind
witte pupil
slechte pupil reflex
scheel kijken

24
Q

diagnose retinoblastoom

A

oftalmologisch onderzoek

MRI

25
Q

behandeling retinoblastoom

A

chemo
laser
enucleatie oog

26
Q

symptomen soft tissue sarcomen

A
vervelende gezwellen neus, farynx, uitgang blaas
->
proptose
neusobstructie/bloeding
obstructie keel
obstructie blaas
27
Q

diagnose soft tissue sarcomen

A

radiologie

biopsie

28
Q

behandeling soft tissue sarcoom

A

chemo
RT
HK