Lecture 6 9/25/23 Flashcards
What are the three gram positive cocci of importance?
-staphylococcus
-streptococcus
-enterococcus
What are the general characteristics of staphylococcus bacteria?
-often commensals of skin and mucous membranes
-can cause primary and opportunistic infections
-can be contagious
-seen in nosocomial infections
What are the characteristics of staphylococcus virulence?
-classified based on coagulase enzyme
-coagulase pos. bacteria are more virulent than coagulase neg. bacteria
Which three coagulase positive bacteria are important for this class?
-Staph. aureus
-Staph. hyicus
-Staph. pseudintermedius
How do staph. bacteria invade the body?
through broken skin or mucous membranes
How do staph. bacteria cause damage?
-inflammation
-destruction of neutrophils
-pus formation
Which staph. species cause purulent infections in dogs and cats?
-S. pseudintermedius
-S. aureus
Which staph. species is the most common isolate from canine pyoderma?
S. pseudintermedius
Why are dogs highly susceptible to purulent staph. infections?
thin skin that can easily be invaded
Which staph. species causes greasy pig disease/exudative epidermititis?
Staph. hyicus
What staph. species causes mastitis in cattle?
S. aureus
What is botryomycosis?
a chronic pyogranulomatous inflammation caused by S. aureus
How does pyogenic inflammation differ from pyogranulomatous inflammation?
-pyogenic inf. involves lots of neutrophils/pus
-pyogranulomatous also involves macrophage pus in addition to neutrophils
What staph. species causes bumble foot/chronic pododermatitis in poultry?
S. aureus
Which toxin-mediated diseases occur in humans as a result of superantigen effects?
-staphylococcal toxic shock syndrome
-staphylococcal food poisoning
-staphylococcal scalded skin syndrome
What types of infections are coagulase-neg. staph. species involved in?
-nosocomial
-UTI
-colonization of catheters and implants
How can staph. species be diagnosed in the lab?
-cytology or gram staining
-routine aerobic culture
-PCR/molecular detection
What is the limitation associated with using PCR to detect staph.?
staph. is a common commensal and may result in a false positive even if it is not causing the disease
Why is it important to identify the underlying disease states with staph. infections?
staph. are primarily opportunistic, so just treating the bacterial infection will not fully resolve the problem