Lecture 15 10/26/23 Flashcards
What are the characteristics of Moraxella bovis?
-causes infectious bovine keratoconjunctivitis
-can lead to corneal ulceration, edema, and permanent blindness
How is Moraxella bovis diagnosed?
-culture
-PCR
How is Moraxella bovis treated?
-isolation
-antimicrobials
-supportive therapy
-anti-inflammatories
How is Moraxella bovis controlled?
-control of predisposing factors
-bacterin vaccination
What are the general characteristics of Brucella sp.?
-public health significance
-infection through ingestion, inhalation, direct contact, or venereal transmission
-can survive outside of host for months
-causes abortion and febrile, chronic granulomatous disease
What are the virulence factors/properties of Brucella sp.?
-facultative intracellular
-enhanced growth in repro. organs of sexually mature hosts
What are the characteristics of Brucella abortus?
-geographic disease
-causes abortion, embryonic death, epididymitis, orchitis, and bursitis
-young animals resistant
-infected adults remain infected for life
-cellular immunity protects against disease but does not clear infection
What are the characteristics of Brucella abortus treatment and control?
-reportable
-treatment not practical
-live strain vaccine available
-federal test-and-slaughter program in place
What are the characteristics of Brucella abortus in horses?
-rare
-poll evil-septic arthritis of atlantoccipital jnt
-fistulous whithers/supraspinous bursitis
What does Brucella suis cause in feral swine and hunting dogs?
severe orchitis
What are the characteristics of Brucella canis?
-transmitted during breeding
-can remain bacteremic for years
-testicular swelling and epididymitis
-infertility and abnormal sperm count
-late term abortions
-uveitis and diskospondylitis
How is Brucella canis diagnosed?
-blood culture (gold standard)
-serology tests
What are the characteristics of Brucella canis treatment and control?
-several weeks of antibiotic therapy
-spay/neuter can reduce transmission
-prostate and testicle chronically infected
-test and eliminate is only proven control
What disease is caused by Brucella sp. in humans?
undulant fever/Bang’s disease
Which Brucella species is NOT known to cause disease in humans?
Brucella ovis