lecture 3 & 4 Flashcards

1
Q

define residual volume

A

the volume of gas in the lungs at the end of maximal expiration

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2
Q

define tidal volume

A

the volume of air breathed in or out of the lungs at each breathe

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3
Q

define expiratory reserve volume

A

the maximum volume of air that expelled from the lungs at the end of normal expiration

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4
Q

define inspiratory reserve volume

A

the maximum volume of air that can be drawn into the at the end of a normal inspiration

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5
Q

define vital capacity

A

tidal volume + inspiratory reserve volume +expiratory reserve volume

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6
Q

define total capacity

A

vital capacity plus the residual volume

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7
Q

define ispiratory capacity

A

tidal volume + inspiratory reserve volume

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8
Q

define functional residual capacity

A

expiratory reserve volume + residual volume

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9
Q

what is FEV1

A

forced expired volume in 1 second

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10
Q

what is FEV1:FVC

A

fraction of forced vital capacity expired in 1 second

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11
Q

what does ventilation mean

A

broadly and simply ventilation refers to movement of air into and out of the lungs

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12
Q

What are the 2 types of ventilation

A

pulmonary ventilation and alveolar ventilation

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13
Q

describe what pulmonary ventilation is

A

total air movement into/out of lungs

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14
Q

describe what alveolar ventilation is

A

FRESH air getting to the alveoli and therefore available

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15
Q

what is atmospheric pressure (value)

A

760mmHg

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16
Q

what is the partial pressure of oxygen (value)

A

160mmHg

17
Q

during hyperventilation will alveoli ventilation increase or decrease

A

increased alveolar ventilation as Po2 rises to 120 and Pco2 falls to 20

18
Q

during hypo ventilation will alveolar ventilation increase or decrease

A

decrease as Po2 falls to 30 and Pco2 rises to 100

19
Q

surfactant is produced by alveolar cells why is it useful to alveoli

A

surfactant reduces tension on alveolar surface membrane thus reducing tendency for alveoli to collapse

20
Q

when does sufactant production start during pregnancy

A

25 weeks gestation

21
Q

when is surfactant production complete

A

by 36 weeks

22
Q

what stimulates surfactant production

A

thyroid hormones and cortisol (which increase towards the end of pregnancy

23
Q

what does compliance mean/represent

A

it represents stretchability of the lungs

24
Q

define high compliance

A

large increase in lung volume for small decrease in ip pressure

25
Q

define low compliance

A

small increase in lung volume for large decrease in ip pressure

26
Q

what is emphysema

A

loss of elastic tissue - means expiration requires effort

27
Q

alveolar ventilation declines in what direction in the lungs

A

declines with height from the base to the apex

28
Q

compliance also declines in the lungs, what pattern does this follow

A

compliance declines with height from the base to the apex due to alveoli at the apex being more inflated at FRC. At the base alveoli are more compressed

29
Q

a small change in pressure will bring about a larger change in volume where, the base or the apex

A

the base

30
Q

define anatomical dead space

A

the volume of air taken in during each breathe the does not mix with the air in the alveoli

31
Q

physiological dead space includes alveoli that are ventilated but not perfused with blood. True or false?

A

True