Cystic fibrosis in Adults Flashcards
On average how long does a person with cystic fibrosis live for
around 37 years
what health problem do 80% of adults suffer from
recurrent pulmonary infections and pancreatic insufficiency
what health problem do 5% of adults with CF suffer from
gastrointestinal problems ONLY
what is Bronchiectasis
abnormal widening of the bronchi or their branches, causing a risk of infection.
what usually causes Bronchiectasis in patients with CF
bacteria build up causes an inflammation response leading to bronchieactasis
if a patient has Bronchieactasis what else are they likely to have
haemoptysis
if there is a lot of blood being coughed up due to haemoptyisis what can be done
a catheter can be put in and can block off any bleeding vessels
in CF patients what usually ends up killing them
recurrent pulmonary infections and pancreatic insufficiency
what are the symptoms of type 1 respiratory failure
decrease PaO2
what are the symptoms of type 2 respiratory failure
decreased PaO2
increased PaCO2
what are the bacterial pathogens most likely to infect a patient with CF
Psedomonas aeruginosa 60%
staphylococcus 40%
where domestically can you find pseudomonas
shower head “gunge” where it forms a biolayer
what is the natural habitat for pseudomonas
in the soil
normally what role would CFTR play in reaction to Pseudomonas entering the lungs
usually plays a role in endocytosis and destruction
why is it difficult for white blood cells to fight off pseudomonas in the lungs once they are colonised
as it produces a bio film to protect itself from the hosts defense’s
