Lecture #29 - Chemical digestion Flashcards

1
Q

Chemical digestion:

  1. The chemical hydrolysis of food by enzymes are secreted by what three things?
  2. And also hydrolysis by enzymes attached to ______ (contact digestion)
  3. What are the main nutrients that undergo chemical digestion? (3)
  4. Why break them down>
A
  1. Because they’re too big. And once break down, the proteins can recognise them and bring them into epithelium
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2
Q

Carbohydrates:

  1. Just know that this is the main and i_____ source of energy (but how much do we eat?)
  2. Consist of chains of m_____ and _____ is a typical monosaccharide
A
  1. Important
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3
Q

Composition of ingested carbohydrates:

  1. What two main carbohydrates in diet?
  2. They are _____ polysaccharides
  3. What’s their bond?
  4. Okay, cellulose - ____ polysaccharide, what bond? Can we digest? What does it provide and what does it not provide?
  5. We also digest disaccharides - what are the of them?
  6. Do we ingest monosaccharide?
A
  1. Only a limited amount
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4
Q

Proteins:

  1. How much do we ingest in our food?
  2. The intestine also has to digest an equivalent (70/100g per day) amount of ____ ____ such as enzymes and immunoglobins
  3. Required for the ____ ____
    - 20 of them
    - How many are essential?
  4. What bond links them?
A

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5
Q

Lipids:

  1. How much consumed?
  2. Consist mainly of what?
    - contains fat soluble _____ (what are the 4?)
  3. What are the components of triglycerides and what bond?
  4. Fatty acids have variable chain lengths - leads to different ____
A
  1. Properties
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6
Q

Just to reiterate, why do we need chemical digestion?

A

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7
Q

Digestive enzymes (carry out chemical digestion)

  1. Are e_____
  2. Are o____ c_____
  3. Are s____
    - Will only act on specific _____
    - Require different enzymes for different ____
  4. Function optimally at specific ____
A

-

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8
Q

Chemical digestion is a two step process:

  1. L____ digestion
    - initial digestion involving enzymes secreted into ____
    - what is released by salivary glands, stomach, and in SI? (by pancreas)
  2. C____ digestion
    - Digestion completed by enzymes produced by ____
    - There enzymes are attached to what of enterocytes?
    - So substrates/molecules need to…
    - So at the brush border (microvilli), the huge SA helps with increasing amount of enzymes as well as a___
A
  1. ….come into contact with them
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9
Q

Chemical digestion of carbohydrates

  1. Luminal digestion: salivary and pancreatic (double hit bc….) digest and convert polysaccharide into what?
  2. Contact digestion: what are the disaccharides broken down into?
    - By what?
A

-

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10
Q

Chemical digestion of proteins:

  1. Luminal digestion:
    - involves what 3 enzymes and where are they secreted?
    - Convert proteins into p___ and p____ (which is…)-
    - . What two places does it occur?
  2. Contact digestion:
    - involves _____
    - attahced to what?
    - ____ types (specific for different short chain proteins)
    - convert polypeptides into individual ___ ___
    - since they enzymes are right on epithelium, the cell can what?
A
  1. Last bit - absorb good bc right next to it
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11
Q

Chemical digestion of lipids:

  1. All in L____
    - so no c____ digestion
  2. Digestive enzymes are dissolved in _____ fluid so can cause problems for fats because?
A

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12
Q

What are the 4 overall steps for chemical digestion of lipids?
What is emulsification and stabilisation (in yellow)

A

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13
Q

1 Emulsification of lipids:

  1. What separate large fat droplets into smaller droplets? (how many micrometes are the smaller droplets)
  2. What does this do to the SA?
  3. Where does it occur in? (2)
A

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14
Q

2 Stabilisation of lipids:

  1. What two things are involved?
  2. What fluid are they secreted into?
  3. Stabilise the _____ droplets
  4. Allow for formation of ____ droplets
    - increase sA even more
  5. Where does this occur?
A

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15
Q

3: Hydrolysis of lipids:

  1. Occurs where and at the surface of what?
    - no contact digestion!
  2. Involves what enzyme and what is its cofactor and they’re both released by?
  3. Co-lipase ____ lipase to surface of emulsion droplet
  4. Lipase concretes TAGs to what two things? What bonds are broken?
A

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16
Q

4 Formation of micelles:

  1. Products are insoluble esp monoglycerides and long chain FA so keep in solution through formation of what?
  2. What are micelles
    - ___ droplets (diameter?)
    - how many molecules and what are they?
A

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