Lecture 2 Flashcards

0
Q

meiosis

A

crossing over and independnt assortment and fertilization

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1
Q

2 ways to get genetic variagtion

A

mutaion and sexual reproduction… mutation only way to get new information

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2
Q

the production of haploid gametes

A

meiosis

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3
Q

the fuiosn of haploid gametes

A

fertilization

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4
Q

consequences of meiossi

A

genetic variation

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5
Q

interphase

A

DNA synthesis and chromosomes replication phase

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6
Q

seperation of homologous chromosome pairs, and reduction of the chromosome number by half

A

meiosis 1

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7
Q

seperation of sister chromatids, also known as equational division

A

meiosis II

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8
Q

major results of meiosis

A

increase in cell numbers sometimes, duaghter cells are not genetically identical, daugther cells are haploid, formation of gametes… compare to mitosis

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9
Q

gametognesis

A

spermatogensis. oogenesis… produces sperm and eggs

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10
Q

synapsis

A

pairing of homologous chromosmes

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11
Q

crossing over

A

in meiosis

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12
Q

meiosis requires

A

two consectutive cell divisions but only one cycle of DNA replication

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13
Q

crossing over

A
  1. once chromosome possesses the A and B allele
  2. and the homologous chromosomes possesses the a and b allele
    DNA SYNTHESIS
  3. DNA replication in the S phase produces identical sister chromatids
    CROSSING OVER
  4. During crossing over in prophase I, segments of nonsister chromatids are exchanged.
    MEIOSIS I AND II
  5. after meiosis I and II, each of the resulting cells carries a unique combination of alleles
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14
Q

produces variation without crossing over

A

independent assortment… needs more than on pair of chromsomes… line up as homologous pairs in varies ways.

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15
Q

reduction divison

A

meiosis I…. Diploid to haploid

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16
Q

equational division

A

Meiosis II… haploid

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17
Q

prophase I

A
Leptotne
zygotene
pachytene... synaptonemal complex
diplotene.. bivalent or tetrad, chiasmata
diakinesis
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18
Q

leptotene

A

exteneded state, microscopically can’t be discerned as indviduals… thread like, very thin, each chormosome still two chromatids(replication has already occured)… start to condense…

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19
Q

zygotene

A

start ot pair up, homologous chromsomses pair(synapsis).. synaptonemal complex forms, results in bivalents(tetrads)

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20
Q

pachytene

A

thick… starting to condense.. shorter and thicker… crossing over begins

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21
Q

synaptonemal complex

A

later like structure btw to chromosomes… alignment mechanims… if this does not work correctly duplicaiton and deletion occurs… equal crossing overs.

22
Q

diplotene

A

start to see tetrads(bivalents)

seee cross over points, chiasmata(pt where crossover occurs) are well defined

23
Q

diakinesis

A

cross over points start to move toward the end… homoloug pair and crossing over. termilalization occurs. spidle apparatus in place. nuclear memnbrane disrupted

24
metaphase I
Centromeres DONOT divide, random alignment of homologus pairs of chromosomes along the metaphase plate
25
prophase I
synopsis... pair up.
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anaphase I
move to opposite poles... not idintical bc of crossing over... haploid.... second mechanism of generating genetics variation in the newly formed gamates
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Telephase I
cytokinesis occurs, neclear membrane reforms. spinndle apparatus disassembles... HAPLOID.... INterkinesis...
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interkinesis
nucler membranes reform, spindle apparatus disassembles, chromsomes may uncoil to vaying degress... spindle usually breaks down.... no DNA synthesis takes place
29
prophase II
chromsomes condense... each chromosmes has 2 chromatids... nuclear membrane disapears, each chromosmes has two chromatids ...e ach daughter cell has one complete set of chromosomes (haploid)
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metaphase II
chromosmes line up on equtorial plate... kinetochoroes face opposite poles...
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anaphase II
centromeres have split... sister chromatids seperate... chromosmes move to opposite poles... each consists of single chromatid
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telophase II
chromosmes uncoil, Four geneticall unique haploid cells!!! 4. is one compelte set... cytokinesis is complete. nuclear membre reforms.spindle aparatus disintigrates ... chromosomes arrive at the spindle poles.
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cytokinesis meiosis
the cytoplasm divides to produce tow cells, each having half the orginal number of chromosomes
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cohesion.
holds chromatids together during early parts of mitosis... break down allows sister chromatids to spearate during mitosis anaphase
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cohesion during meiosis
chromosomes arms holds homologous chromsomes together at chiasmata through metaphase I
36
meiosis specific cohesions at centromere ...
keeps sister chromatids together during anaphase...
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the cohesion that protects anaphase of sister chromatids during meiosis is
shugoshin
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separase
kept inactive during interphase and early mitosis, breaks down cohesion at end of metaphase, breakse down meiosis-specific cohesion at centromere during end of metaphase II
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Keeps separase inactive during interphase and early mitosis
securin
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keeps sists kinetochores oriented toward same pole during metaphase i
monopolins
41
48 mins
in lecture 2
42
spermatogonia--->
...
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spermatogenesis... primordial germ cells
diploid... divide mitotically to produce dipoloid spermatogonia
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spermatogonia are
diploid can undergo repereated rounds of mitosis to produce more spermatogonia may initiate meiosis and enter into prophase I to give rise to primary spermatocyte
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Sour of genetica variation
mutation and sexual reproduction
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meiosis includes
crossing over and independent assortment and fertilization
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Spermatogonia-->
primary spermatocytes 2N
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primary spermatocytes 2N 1-->
secondary spermatocytes N 2... haploid, undergo meiosis II to produce haploid spermatids
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secondary spermatocytes 2.... N-->
4 spermatids N... haploid, differentiate into haploid sperm
50
oogonia-->
2n primary oocytes.... arrests at diploteme of prophase I
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Primary ooctye 2N-->
seondary oocyte.... willl also divide off polar body... will go to 2nd metaphase that is ovulated and stop unless fertilized...
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secondary oocyte fertilized
ootid and polar body
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primary oocyte
lg ovum and small polar body, meiosis will not re