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Microbiology 2 > Lecture 10: Poxviruses, papillomaviruses, African Swine fever > Flashcards

Lecture 10: Poxviruses, papillomaviruses, African Swine fever Flashcards

1
Q

What are some examples of orthopoxviruses

A
  1. Camelpox
  2. Monkeypox
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2
Q

what are some examples of capripoxviruses

A
  1. Sheep/goat pox
  2. Lumpy skin disease
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3
Q

what are some examples of leporipoxviruses

A

rabbit myxoma virus

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4
Q

what poxviruses are the foreign animal diseases

A
  1. Camelpox
  2. Monkeypox
  3. Sheep/goat pox
  4. Lumpy skin disease
  5. Rabbit myxoma virus
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5
Q

poxviruses are the largest viruses >__nm

A

200

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6
Q

In poxviruses where does DNA replication occur

A

in cytoplasm

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7
Q

what is the main clinical sign of poxviruses

A

vesicles and scabbing

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8
Q

what this, what is an important differential

A

Dx: bovine papular stomatitis

Important ddx: FMD

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9
Q

T of f: bovine papular stomatitis is only in U.S.

A

false- worldwide distribution

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10
Q

T or F: bovine papular stomatitis is zoonotic

A

true

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11
Q

what this

A

orf/contagious ecthyma

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12
Q

T or f: orf/contagious ecthyma has worldwide distribution

A

true

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13
Q

what wrong and what type of virus

A

Myxomatosis
Pox virus

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14
Q

what wrong

A

lumpy sign disease

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15
Q

What pox virus is this. from sheep

A

sheep/goat pox

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16
Q

what lesions are associated with sheep and goat pox

A

dermal/pulmonary

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17
Q

what this

A

Camelpox

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18
Q

t or f: Camelpox is a foreign animal disease in old world camelids

A

true

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19
Q

how are poxviruses transmitted

A
  1. Aerosol
  2. Vector- mechanical
  3. Direct contact
  4. Fomites
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20
Q

What is tx for poxviruses

A

palliative care

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21
Q

how are poxviruses prevented and controlled

A
  1. Vaccination
  2. Control mechanical vectors
  3. Isolation/slaughter
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22
Q

what tissue does cowpox target

A

oral mucosa

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23
Q

how is cowpox transmitted

A

contact, fomites, vectors

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24
Q

is cowpox a FAD and zoonotic

A

not FAD, yes zoonotic

25
Q

is orf a FAD and zoonotic

A

not FAD, yes zoonotic

26
Q

what tissue does orf target

A

oronasal mucosa

27
Q

how is orf transmitted

A

contact, fomites, vectors

28
Q

is myxomatosis a FAD and zoonotic

A

yes FAD, not zoonotic

29
Q

what does myxomatosis target

A

skin, lymphocytes

30
Q

how is myxomatosis transmitted

A

contact, fomites, vectors

31
Q

is lumpy skin disease a FAD and zoonotic

A

yes FAD, no zoonotic

32
Q

where does lumpy skin disease target

33
Q

how is lumpy skin disease transmitted

A

contact, fomites, vectors

34
Q

is sheep/goat pox a FAD and zoonotic

A

yes FAD, not zoonotic

35
Q

where does sheep/goat pox target

A

skin, URT/LRT

36
Q

how is sheep/goat pox transmitted

A

contact, fomites, vectors

37
Q

is Camelpox an FAD and is it zoonotic

A

yes FAD, zoonotic but rare

38
Q

where does Camelpox target

A

skin, URT/ LRT

39
Q

how is Camelpox transmitted

A

contact, fomites, vectors

40
Q

is sealpox an FAD and zoonotic

A

not FAD, yes zoonotic

41
Q

where does sealpox target

A

skin, mucosa

42
Q

how is sealpox transmitted

A

contact, fomites

43
Q

poxviruses replicate in the __, most commonly in __ tissues

A

cytoplasm, dermal/mucosal tissues

44
Q

what is the cause of equine sarcoidosis

A

bovine papilloma virus

45
Q

how do papillomaviruses get into cells

A

endocytosis within basal squamous epithelial cells

46
Q

what are the clinical signs of papillomaviruses

A

proliferative lesions (warts) of the epithelium

47
Q

what virus caused this

A

Papillomavirus

48
Q

what is tx for papillomavirus

A
  1. Excision
  2. Cryosurgery
  3. Radiation, chemo
  4. Spontaneous regression
49
Q

how and where do papillomaviruses replicate and how does that help them evade immune system

A

within nucleus of epithelial cells, through a non-lytic process which avoids triggering the immune system

50
Q

Where was African swine fever found 1921-2007

A

african subcontinent

51
Q

where is African swine fever found from 2007- present

A

eastern, Western Europe, Asia, Haiti, DR

52
Q

African swine fever is the only known DNA virus with ___

A

biological arthropod vector

53
Q

what are the per acute clinical signs of African swine fever

A

sudden death

54
Q

what are the acute signs of African swine fever and mortality

A

fever, ADR, cutaneous hemorrhage, splenomegaly

High mortality

55
Q

what are the signs of subacute African swine fever and mortality

A

pneumonia, weight loss, joint swelling, ADR
Variable mortality

56
Q

how is African swine fever transmitted

A

tick borne, contact with infected swine or pork products

57
Q

what is the treatment and prevention for African swine fever

A
  1. Depopulation/ decontaminate/ repopulate
  2. Prevent exposure to wild or feral swine, insect vectors
58
Q

there are no effective vaccines for African swine fever, it is __incompatible

59
Q

what does DIVA mean

A

ability to distinguish infected from vaccinated animals- requirement for effectively separating true infections from animals which have been vaccinated in endemic areas

Microbiology 2 (24 decks)

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