Lecture 1 Flashcards
Human embryonic development takes an average of ____________ and is composed of two stages __________
38 weeks.
- embryonic period
- Fetal period
First 8 weeks of embryonic development is called _______________
Embryonic Period
remaining 30 weeks of embryonic development is called___________________
Fetal Period.
_________ develops in ovary.
Oocyte
After ovulation, THE Oocyte IS transported to ______ by __________________
uterus, uterus by muscular contractions of the fallopian tube and the cilia lining the tube.
Oocyte is a _________ cell
haploid cell, containing only 1 copy of each chromosome
The Oocyte remains ______ within the fallopian tube for approximately 12 hours.
viable
The oocyte is surrounded by a ___________, a thick extracellular matrix called ___________
plasma membrane
zona pellucida
The additional layer of cells that surround the oocyte
the corona radiata.
Sperm are___________ and are attracted to the oocyte.
haploid cells
Sperm ______________ a pathway through these membranes to fertilize the oocyte.
enzymatically digest
Critical that only one sperm fertilizes the oocyte, and all others are inhibited______________ after the first sperm has entered
by chemical changes
induced in the zona pellucida
Unequal contribution of cytoplasm -
small amount of cytoplasm derived from the sperm compared
to the enormous amount derived from the oocyte.
Sperm and oocyte contribute
equal amounts of genetic material
Nuclear fusion takes ______________
approximately 12 hours
______________ the formation of a single diploid cell from the two haploid cells oocyte and sperm
nuclear fusion
24 hr after fertilization the __________ forms from _________
mammalian zygote, cleavage
___________ the series of mitotic divisions by
which the enormous volume of egg cytoplasm is divided into smaller cells.
cleavage,
Cells formed by cleavage divisions are called _____________
blastomeres.
As cleavage continues, more cells are formed. ______________ continues to surround the cells,
maintaining a constant diameter of the embryo.
The zona pellucida
At the 16-32 cell stage, the embryo is called __________
a morula.
During morula stage, Initially dividing cells are round, but then
become compacted with junctions between them.
• Embryo differentiates into ___________________
external and internal cells
Sphere of ________________ will become the embryonic contribution to the placenta.
external cells
Inside the sphere are a small number of__________ that give rise to the embryo.
internal cells
External cells differentiate into _________ and continue to divide and secrete fluid into the
middle of the morula to create the ___________
trophoblasts
blastocyst cavity.
Internal cells are compacted into the_____________
inner
cell mass.
As the blastocyst expands, the_______ degenerates, in preparation for ________________
zona pellucida
implantation
The __________ keeps developing embryo from attaching to fallopian tube lining until it reaches the uterus.
zona pellucida
Fertilization usually occurs in the ______________
lateral third of the fallopian tube.
By day 3, the embryo is a
compact ball of cells. By day 4, it contains about 60 cells and has reached the uterus. Fluid is secreted
into the middle of the morula forming a _________
blastocyst.
After the zona pellucida degenerates, trophoblast cells adhere to, and burrow into __________
the lining of the
uterus or endometrium.
Trophoblast cells proliferate and form two layers:
one maintains cellular membranes around the
embryo
the other fuses into a multinucleated mass,that invades the uterine lining.
the other fuses into a multinucleated mass ___________ that invades the uterine lining.
syncytium,
After the blastocyst is deeply embedded in the uterine lining, “holes” form in the outer trophoblast
layer and __________________
fill with maternal blood. Embryo is now in contact with its source of nourishment
Placenta is derived from both
embryonic trophoblast and maternal endometrial cells.