Langerhans cell histiocytosis Flashcards
1
Q
What is langerhans cell histiocytosis?
A
rare condition associated with the abnormal proliferation of histiocytes
2
Q
When does LCH typically present?
A
Childhood
Presents with bony lesions
3
Q
Clinical features in LCH
A
bone pain (skull or proximal femur)
cutaneous nodules
recurrent otitis media/mastoiditis
4
Q
Electromicroscopy findings
A
tennis racket-shaped Birbeck granules
5
Q
Typical radiological findings on skull XR
A
- ‘punched out’ osteolytic lesions with scalloped edges
- usually seen in the bilateral parietal regions
- lesions have a characteristic bevelled edge.
6
Q
A
