Behcet's syndrome

Question 1

What is Behcet’s syndrome?

Answer 1

complex multisystem disorder
- presumed autoimmune-mediated inflammation of the arteries and veins

Question 2

Classic triad in Behcet’s

Answer 2

oral ulcers
genital ulcers
anterior uveitis

Question 3

Common demographics for Behcet’s

Answer 3

more common in the eastern Mediterranean (e.g. Turkey)
more common in men
young adults (e.g. 20 - 40 years old)
associated with HLA B51
30% of patients have a positive family history

Question 4

Other clinical features

Answer 4

classically: 1) oral ulcers 2) genital ulcers 3) anterior uveitis
thrombophlebitis and DVT
arthritis
neurological involvement (e.g. aseptic meningitis)
GI: abdo pain, diarrhoea, colitis
erythema nodosum

Question 5

There is no definitive diagnostic test for Behcet’s. TRUE/FALSE?

Answer 5

TRUE
diagnosis is based on clinical findings