Lab: Blood + Blood Pressure Flashcards
Blood pressure
Force exerted by blood on the blood vessel wall
Laminar flow
refers to the streamline movement of blood
Turbulent blood flow
Cause by constriction of the vessel than disrupts laminar flow
Where is blood pressure the highest?
Aorta and large elastic arteries
As arteries branch and as blood travels farther from the heart BP…
decreases
Sphygmomanometer
- Inflatable blood pressure cuff and pressure gauge
- Measures systolic and diastolic blood pressure
Sounds heard via stethoscope
korotkoff sounds
Which artery do you use the sphygmomanometer at?
Brachial artery
1st loud korotkoff sound
- systolic BP
- Turbulent flow of blood
Last faint korotkoff sound
- Diastolic BP
- Laminar flow of blood
Normal systolic pressure
120 mmHg
Normal diastolic BP
80 mmHg
3 principal elements of the cardiovascular system
Heart
Blood Vessels
Blood
Function of the cardiovascular system
Transport: oxygen, nutrients, and hormones
Remove: carbon dioxide, heat, and waste
How much blood does the average adult body contain?
5.5 L
What percent of your body weight does blood make up?
8%
What percent of whole blood is plasma?
55%
What percent of whole blood is formed elements?
45%
What forms formed elements?
- Erythrocytes (RBC)
- Leukocytes (WBC)
- Thrombocytes (platelets)
What percent of plasma is water?
91.5%
What percent of plasma is solutes/proteins?
8.5%
Thrombocytes description
Fragments of megakaryocytes
Aid in clotting
Anucleate (no nucleus)
Very small
Function of thrombocytes
Aid in clotting
Erythrocyte description
Produced in red bone marrow
Anucleate
Contain hemoglobin
What gives erythrocytes their red color?
Hemoglobin contains heme which is a red pigment
polycythemia
abnormally high number of RBCs
Erythropoietin
Hormone that stimulates RBC production
Anemia
Deficiency of RBCs or hemoglobin that results in inadequate oxygen supply
Leukocytes
Nucleates cells that attack pathogens and foreign substances in the body
Granular leukocytes
- Neutrophils
- Basophils
- Eosinophils
Agranular leukocytes
- Monocytes
- Lymphocytes
Leukocytosis
High number of functional WBCs
Leukopenia
Low number of functional WBCs
Granular
Multi-lobes
60-70% of leukocytes
Neutrophil
What is the”first responder” to an infection site
Neutrophil
Which leukocyte has an important role in inflammation and bacterial infection?
Neutrophil
Agranular
Large nucleus
Small cytoplasm
25-33% of leukocytes
Lymphocyte
Which leukocyte is mostly found in the lymphatic system?
lymphocyte
Which leukocyte has a role in viral infections, cancer, and parasitic infections?
Lymphocyte
Agranular
Largest WBC
Amorphous
Kidney shaped nucleus
3-8% of leukocytes
Monocyte
Which leukocyte has a role in viral infections and inflammation?
Monocytes
Granular
Bi-lobed
Big, pink granules
2-4% of leukocytes
Eosinophil
Which leukocyte has a role in allergic reactions, parasitic infections, and autoimmune diseases?
Eosinophil
Granular
Dark purple granules
No visible cytoplasm
Less than .5 of leukocytes
Basophil
Which leukocyte has a role in allergic reactions, cancer, and hypothyroidism?
Basophil
Which two enzymes are stored in basophil granules?
Histamine (vasodilator)
Heparin (anticoagulant)
In a WBC differential, which leukocyte is up if a bacterial infection is present?
Neutrophil
In a WBC differential, which leukocyte is up if a viral infection is present?
Lymphocyte
In a WBC differential, which leukocyte is up if a viral infection with inflammation is present?
Monocyte
In a WBC differential, which leukocyte is up if a parasite or allergy is present?
Eosinophil
In a WBC differential, which leukocyte is up if an allergy is present?
Basophil
Differential WBC
A test that determines a percentage of each of the five types of WBCs in a sample
Hematocrit
Percentage of erythrocytes in a whole blood sample
Normal female hematocrit values
37-48%
Normal male hematocrit value
42-52%
Hematocrit =
( length of RBCs / length of all components ) x1 00