L7: Fetal & Neonatal Asphyxia Flashcards
Def of Fetal Distress (Intrauterine - Fetal Asphyxia)
- State of inadequate oxygenation & inadequate elimination of CO2 that results in metabolic acidosis if persists for long time.
Types of Fetal Distress (Fetal Asphyxia)
Etiology of Acute Fetal Distress (Intrapartum Asphyxia)
- Maternal
- Fetal
- Placental
- Cord
Etiology of Acute Fetal Distress (Intrapartum Asphyxia)
- Maternal Causes
Maternal Causes of Acute Fetal Distress
- Hypoxic Anoxia
Due to
- pulmonary obstruction
- pulmonary TB
- bilateral pneumonia
- prolonged anesthesia
- convulsive fits.
Maternal Causes of Acute Fetal Distress
- Stagnant Hypoxia
Due to:
- HF
- pulmonary edema
- severe shock.
Maternal Causes of Acute Fetal Distress
- Anemic Anoxia
Due to:
- severe anemia (from Hge).
Maternal Causes of Acute Fetal Distress
- Histotoxic Anoxia
As in
- barbiturate poisoning
Causes of Acute Fetal Distress
- Fetal
- Cerebral edema & ischemia from prolonged labor or difficult forceps (due to ICH or depressed skull fractures).
Causes of Acute Fetal Distress
- Placental
- Placental insufficiency
- Placental separation
- Placental compression
Placental Causes of Acute Fetal Distress
- Placental Insufficiency
Due to:
- small placenta
- placental thrombosis
- multiple placental infarcts
- placental aging.
Placental Causes of Acute Fetal Distress
- Placental Separation
As in:
- placenta previa
- accidental Hge.
Placental Causes of Acute Fetal Distress
- Placental Compression
Due to:
- Tetanic uterine contraction
- Prolonged labor after ROM
- Compression by head in placenta previa type lI posterior.
Causes of Acute Fetal Distress
- Cord
- Cord prolapses
- Cord compression
- Hematoma, True knots, or tight coils of cord around fetal neck.
- Avulsion of cord
- Rupture of vasa previa.
Cord Causes of Acute Fetal Distress
- Cord Prolapse
Leading to cord compression & vasospasm of its vessels.
Cord Causes of Acute Fetal Distress
- Cord Compression
- By uterine contraction after drainage of liquor or by forceps blades.
Dx of Acute Fetal Distress
Dx of Acute Fetal Distress
- AF
Meconium-stained liquor in cephalic presentation.
Dx of Acute Fetal Distress
- FHR
Managment of Acute Fetal Distress
- Conservative
- Active
Managment of Acute Fetal Distress
- Conservative
Managment of Acute Fetal Distress
- Active
Other Names of Asphyxia Neonatorum
- Extrauterine or Postnatal Asphyxia
Def of Asphyxia Neonatorum
- Failure of establishment of good pulmonary circulation & respiratory function after birth.
Normal Physiology of Respiration after birth
Etiology of Asphyxia Neonatorum
Etiology of Asphyxia Neonatorum
- CNS Failure
Etiology of Asphyxia Neonatorum
- Peripheral Failure
Complications of Asphyxia Neonatorum
Dx of Asphyxia Neonatorum
- APGAR Score
- Clinical Picture
Def of APGAR Score for Asphyxia Neonatorum
Clinical score to assess degree of neonatal asphyxia & effectiveness of resuscitation
APGAR Score for Asphyxia Neonatorum
- Technique
- The scoring system includes 5 items & each item takes 0, 1 or 2 so, full mark is 10/10 (HR, Respiration, Reaction, Color, Tone).
APGAR Score for Asphyxia Neonatorum
- Scoring
APGAR Score for Asphyxia Neonatorum
- Time
Score is done at 1 & 5 minutes.
- 1 minute score: Correlates well e survival.
- 5 minutes score: Prognostic index of late CNS damage at 1 year of age.
APGAR Score for Asphyxia Neonatorum
- Interpretation
- Score of 7-10: Good condition.
- Score of 4-6: Moderate asphyxia.
- Score < 4: Severe asphyxia.
CP of Asphyxia Neonatorum
CP of Asphyxia Neonatorum
- Asphyxia Livida
CP of Asphyxia Neonatorum
- Asphyxia pallida
Compare between Asphyxia livida & Asphyxia Pallida
Prevention of Asphyxia Neonatorum
- Antenatal
- Intranatal
Prevention of Asphyxia Neonatorum
- Antenatal
Proper ANC to high-risk cases.
Prevention of Asphyxia Neonatorum
- Intranatal
TTT of Asphyxia Neonatorum
TTT of Asphyxia Neonatorum
- Airway
TTT of Asphyxia Neonatorum
- Breathing
TTT of Asphyxia Neonatorum
- Cardiac Massage
TTT of Asphyxia Neonatorum
- Drugs
Drugs in TTT of Asphyxia Neonatorum
- NaHCO3
To correct metabolic acidosis.
Drugs in TTT of Asphyxia Neonatorum
- Epinephrine
- 0.1 ml/kg of 1/ 10000 dilution either by slow IV drip or intracardiac through 4th Lt intercostal space if HR doesn’t respond < 80 bpm).
Drugs in TTT of Asphyxia Neonatorum
- Naloxone
0.1 mg/kg 1 M or IV as an antidote to pethidine or morphine.
Drugs in TTT of Asphyxia Neonatorum
- Ca Gluconate
To stimulate cardiac contractility.
Drugs in TTT of Asphyxia Neonatorum
- Glucose
To prevent or treat hypoglycemia.
Drugs in TTT of Asphyxia Neonatorum
- Volume Expanders
Ringer’s lactate or normal saline can be given to correct hypovolemia.
Drugs in TTT of Asphyxia Neonatorum
- Antibiotics
To guard against pulmonary infections.