L12: Neonatal Sepsis

Question 1

Types of Neonatal Sepsis

Answer 1

• Early Onset Sepsis
• Late Onset Sepsis

Question 2

Time of Early Neonatal Sepsis

Answer 2

In the first 3 days of life

Question 3

Source of Early Neonatal Sepsis

Answer 3

• Transplacental
• Ascending infection
• Aspiration of vaginal secretions

Question 4

Time of Late Neonatal Sepsis

Answer 4

After the first 3 days of life

Question 5

Source of Late Neonatal Sepsis

Answer 5

• Community acquired infection
• Hospital (Nosocomial) acquired infection

Question 6

Late Neonatal Sepsis is associated with …….

Answer 6

Commonly with meningitis

Question 7

RF for Neonatal Sepsis

Answer 7

Question 8

RF for Neonatal Sepsis

• Maternal

Answer 8

Question 9

RF for Neonatal Sepsis

• Neonatal

Answer 9

Question 10

Common Organsims Causing Neonatal Sepsis

Answer 10

Question 11

Common Organsims Causing Neonatal Sepsis

• Gram -ve

Answer 11

• Klebsiella pneumonia “most common”
• Pseudomonas, proteus
• E-coli

Question 12

Common Organsims Causing Neonatal Sepsis

• Gram +ve

Answer 12

• Group B-hemolytic streptococci
• Staph aureus
• Coagulase -ve Staph

Question 13

CP of Neonatal Sepsis

Answer 13

Question 14

Common Presentation of Neonatal Sepsis

Answer 14

Question 15

Dx of Neonatal Sepsis

Answer 15

Question 16

Dx of Neonatal Sepsis

• Labs

Answer 16

Question 17

Dx of Neonatal Sepsis

• Culture

Answer 17

• Blood, Urine, CSF culture
• Local sites e.g. tracheal aspirate, joint aspirate, skin wound

Question 18

Dx of Neonatal Sepsis

• Imaging

Answer 18

Question 19

TTT of Neonatal Sepsis

Answer 19

Question 20

TTT of Neonatal Sepsis

• Early Onset Sepsis

Answer 20

Question 21

TTT of Neonatal Sepsis

• Late Onset Sepsis

Answer 21

• Culture (Blood, (SF, Urine)
• Start Penicillinase-resistant antibiotics (amikacin) or 3ª generation cephalosporin
• Start specific antibiotics … after obtaining culture & sensitivity results

Question 22

TTT of Neonatal Sepsis

• Duration of Therapy

Answer 22