L12: Neonatal Sepsis Flashcards
Types of Neonatal Sepsis
- Early Onset Sepsis
- Late Onset Sepsis
Time of Early Neonatal Sepsis
In the first 3 days of life
Source of Early Neonatal Sepsis
- Transplacental
- Ascending infection
- Aspiration of vaginal secretions
Time of Late Neonatal Sepsis
After the first 3 days of life
Source of Late Neonatal Sepsis
- Community acquired infection
- Hospital (Nosocomial) acquired infection
Late Neonatal Sepsis is associated with โฆโฆ.
Commonly with meningitis
RF for Neonatal Sepsis
RF for Neonatal Sepsis
- Maternal
RF for Neonatal Sepsis
- Neonatal
Common Organsims Causing Neonatal Sepsis
Common Organsims Causing Neonatal Sepsis
- Gram -ve
- Klebsiella pneumonia โmost commonโ
- Pseudomonas, proteus
- E-coli
Common Organsims Causing Neonatal Sepsis
- Gram +ve
- Group B-hemolytic streptococci
- Staph aureus
- Coagulase -ve Staph
CP of Neonatal Sepsis
Common Presentation of Neonatal Sepsis
Dx of Neonatal Sepsis
Dx of Neonatal Sepsis
- Labs
Dx of Neonatal Sepsis
- Culture
- Blood, Urine, CSF culture
- Local sites e.g. tracheal aspirate, joint aspirate, skin wound
Dx of Neonatal Sepsis
- Imaging
TTT of Neonatal Sepsis
TTT of Neonatal Sepsis
- Early Onset Sepsis
TTT of Neonatal Sepsis
- Late Onset Sepsis
- Culture (Blood, (SF, Urine)
- Start Penicillinase-resistant antibiotics (amikacin) or 3ยช generation cephalosporin
- Start specific antibiotics โฆ after obtaining culture & sensitivity results
TTT of Neonatal Sepsis
- Duration of Therapy