L06 - Adaptive Immunity 3

Question 1

why do t cells need antigen presentation

what are APCs and what do they do

what is antigen processing. what does it require

Answer 1

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Question 2

what are the two types of antigen processing pathways. what is the differences, what cells fo each present to

Question 3

endogenous antigens

describe this. what is it and what is involved. what happens

Question 4

tap proteins.

what are they what do they do. for what

Question 5

describe the process in which mhc class i is presented.

where are the antigens from. what types does this include. what other things are involved. what comes from
where

why is this important

Question 6

how can the enodenous antigen thingy be evaded.

which example

Question 7

exogenous antigens

how are the peptides generated and presented and by what

how does the presentation happen

what do the present to

Question 8

how are mhc class ii come about?? structure

ie where does it come from and go

what prevents them from self binding (bonus)

Question 9

what prevents mhc class ii from self binding

and how does it load peptides

what does it activate

Question 10

how can mhc class ii be evaded

4 examples

Question 11

how are t cell antigens kept apart? what are they controlled by and require?

Question 12

recap the t cell dependent b cell respinse