L01 - Overview of Immunity Flashcards
what is antigen and antigen receptor
diff between innate and adaptive immunity
what is effector mechanism
myloid lineage — list and what they do
neutophil - function
phagocytosis
eosinophil - function
?? Helminth infections
monocyte / macrophage
function
monocyte is circulating. macrophage is in tissue.
PHAGOCYTOSIS, ANTIGEN PRESENTATION
dendritic cell
function
antigen presentation
basophil
function
basophil is resident in tissue. the counterpart of this i the mast cell.
?? helminth infecions
lymphoid lineage
what are the cells like. as in physical properties
list them what do they do what type ofn immunity
similary size to rbc. little cytoplasm, few granules
b cells - function
t cells - function
nk cells - function
communication - intercellular signalling
what types
what is used for it how are they defined as
innate antigen receptors
what are key features of them. how do they recognise pathogens
PRR which recognise PAMPS.
genome encoded
non clonally distributed
MBL
what is it how does it work
adaptive antigen receptors key features
b cell structure and features
t cell receptor structure and features
how are adaptive immune receptors generated.
describe the process
v (D) and J gene segments
what is clonal selection
t and b cell memory
the graph. describe it it and what is shows. axis?
what are examples of effector mechanisms
psa
what is adaptive immunity defined by??? its by its receptors boiiii
how to CD8 T cells work?
hint - what helps it out
mhc class I
acute inflammation
what are the features
what does it tell you
what underlies the process
vasodilation, adhesion molecules and increased permeanility.
clinical features defines as an interaction between pathogen and host immunity
