L01 - Overview of Immunity

Question 1

what is antigen and antigen receptor

diff between innate and adaptive immunity

what is effector mechanism

Question 2

myloid lineage — list and what they do

Question 3

neutophil - function

Answer 3

phagocytosis

Question 4

eosinophil - function

Answer 4

?? Helminth infections

Question 5

monocyte / macrophage

function

Answer 5

monocyte is circulating. macrophage is in tissue.

PHAGOCYTOSIS, ANTIGEN PRESENTATION

Question 6

dendritic cell

function

Answer 6

antigen presentation

Question 7

basophil

function

Answer 7

basophil is resident in tissue. the counterpart of this i the mast cell.

?? helminth infecions

Question 8

lymphoid lineage

what are the cells like. as in physical properties

list them what do they do what type ofn immunity

Answer 8

similary size to rbc. little cytoplasm, few granules

Question 9

b cells - function

Question 10

t cells - function

Question 11

nk cells - function

Question 12

communication - intercellular signalling

what types

what is used for it how are they defined as

Question 13

innate antigen receptors

what are key features of them. how do they recognise pathogens

Answer 13

PRR which recognise PAMPS.
genome encoded
non clonally distributed

Question 14

MBL

what is it how does it work

Question 15

adaptive antigen receptors key features

Question 16

b cell structure and features

Question 17

t cell receptor structure and features

Question 18

how are adaptive immune receptors generated.

describe the process

Answer 18

v (D) and J gene segments

Question 19

what is clonal selection

t and b cell memory

the graph. describe it it and what is shows. axis?

Question 20

what are examples of effector mechanisms

Answer 20

psa
what is adaptive immunity defined by??? its by its receptors boiiii

Question 21

how to CD8 T cells work?

hint - what helps it out

Answer 21

mhc class I

Question 22

acute inflammation

what are the features
what does it tell you
what underlies the process

Answer 22

vasodilation, adhesion molecules and increased permeanility.

clinical features defines as an interaction between pathogen and host immunity