ISBT BLOOD GROUP COLLECTIONS (200)

Question 1

Cost collection (205)

Answer 1

• Named after the two patients (Copeland and Sterling) who made anti-Cs^a
• Currently consists of two antithetical antigens, Csa and Csb
• Both Csa and Csb antigens demonstrate a resistance to enzyme treatment

Question 2

Ii collection (207)

Answer 2

• In 2002, the I antigen was promoted to a blood group system 027, leaving i the sole antigen in the collection.
• The i antigen is stronly expressed on cord cells with only trace amounts on adult RBCs (i antigen - abundant in infant RBCs)
• Anti-i is usually IgM reacting at room temperature or 4C

Question 3

Er collection (208)

Answer 3

• High-prevalence Ag: Era and Er3
• Low-prevalence Ag: Erb
• Can be expressed on cord cells
• The antibodies are IgG reacting at the AHG phase and do not fix complement

Question 4

Globoside collection (209)

Answer 4

• Currently consists of one high prevalence antigen: LKE
• Related to the P (003) and Globoside (028) blood group systems

Question 5

MN CHO collection (213)

Answer 5

• Currently consists of six polymorphic antigens:
  1. Hu
  2. M1
  3. Tm
  4. Can
  5. Sext
  6. Sj
• The antigens are associated with the M or N antigen in the MNS (002) system