GENETICS IN BLOOD BANK Flashcards
memorization
How many pairs of chromosomes do humans have?
23 pairs of chromosome
These 23 pairs of chromosomes have:
22 pairs are autosomes
1 pair of sex chromosomes
Male sex chromosome:
Female sex chromosome:
Male sex chromosome: XY
Female sex chromosome: XX
Most blood group genes are inherited as ____________ and are on autosomal chromosomes:
Codominant
ABO gene = Chromosome ____
Rh gene = Chromosome ____
ABO gene = chromosome 9
Rh gene = chromosome 1
Who formulated the laws of inheritance?
Gregor Mendel
It is used in studying gene frequencies in human populations:
Hardy-Weinberg principle
It is the complement of DNA that is inherited (actual genes)
Genotype
Presence of two identical alleles at a particular locus (location)
Homozygous genotype
Different alleles present at a particular locus (location)
Heterozygous genotype
Observable expression of the genotype; description of which antigens are present:
Phenotype
Example of phenotype:
Antigens that are expressed on RBC surface
Type A = A antigens
Tytpe B = B antigens
Type AB = AB antigens
Type O = A & B antigens are absent