I (027) BLOOD GROUP SYSTEM and i ANTIGEN

Question 1

Which Ii antigen is rich in infant RBCs?
Which Ii antigen is rich in adult RBCs?

Answer 1

i antigen - rich in infant RBCs
I antigen - rich in adult RBCs

Question 2

Ii antibody that is mostly IgM, can be auto or allo:

Answer 2

Anti-I

Question 3

Autoanti-I production is stimulated by:

Answer 3

M. pneumoniae (cold agglutinins)

Question 4

Alloanti-I is produced by:

Answer 4

“Adult anti-i” phenotype, IgM/IgG

Question 5

I antibody that is associated with infectious mononucleosis, myeloid leukemia, and alcoholic cirrhosis:

Answer 5

Anti-i

Note: IgG anti-i also been described and has been associated with HDFN

Question 6

An auto-anti-I that interferes with reverse typing:

Answer 6

Benign autoanti-I

Question 7

An autoanti-I that causes vascular occlusion:

Answer 7

Pathogenic autoanti-I