ISBB Flashcards by Deleted Deleted

Q

Cross immunity

A. Edward Jenner
B. Louis Pasteur

A

A. Edward Jenner

*Cowpox, small pox

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Q

Father of Immunology/ First attenuated vaccine

A. Edward Jenner
B. Louis Pasteur

A

B. Louis Pasteur

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Q

Discovey of T cell receptor gene

A. 1798
B. 1880
C. 1901
D. 1984

A

D. 1984

By Tak Wah Mak, Mark Davis

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Q

Serum antitoxin

A. Robert Koch
B. Emil von Behring

A

B. Emil von Behring

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Q

Cellular immunity in TB:

A. Robert Koch
B. Elie Metchnikoff
C. Charles Ricket
D. Jules Bordet
E. Karl Landsteiner
F. Paul Ehrlich

A

A. Robert Koch

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Q

Complement:

A. Robert Koch
B. Elie Metchnikoff
C. Charles Ricket
D. Jules Bordet
E. Karl Landsteiner
F. Paul Ehrlich

A

D. Jules Bordet

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Q

Anaphylaxis:

A. Robert Koch
B. Elie Metchnikoff
C. Charles Ricket
D. Jules Bordet
E. Karl Landsteiner
F. Paul Ehrlich

A

C. Charles Ricket

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Q

Human Blood Group antigens:

A. Robert Koch
B. Elie Metchnikoff
C. Charles Ricket
D. Jules Bordet
E. Karl Landsteiner
F. Paul Ehrlich

A

E. Karl Landsteiner

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Q

Immunity:

A. Robert Koch
B. Elie Metchnikoff
C. Charles Ricket
D. Jules Bordet
E. Karl Landsteiner
F. Paul Ehrlich

A

F. Paul Ehrlich

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Q

Phagocytosis:

A. Robert Koch
B. Elie Metchnikoff
C. Charles Ricket
D. Jules Bordet
E. Karl Landsteiner
F. Paul Ehrlich

A

B. Elie Metchnikoff

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Q

Structure of antibodies:

A. MacFarlane Burnet, Peter Medewar
B. Gerald Edelman, Rodney Porter
C. Rosalyn Yalow
D. George Snell, Jean Dausset, Baruj Benaceraf
E. Niels Jerne

A

B. Gerald Edelman, Rodney Porter

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Q

Discovery of Immunologic tolerance

A. MacFarlane Burnet, Peter Medewar
B. Gerald Edelman, Rodney Porter
C. Rosalyn Yalow
D. George Snell, Jean Dausset, Baruj Benaceraf
E. Niels Jerne

A

A. MacFarlane Burnet, Peter Medewar

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Q

Immunoregulation

A. MacFarlane Burnet, Peter Medewar
B. Gerald Edelman, Rodney Porter
C. Rosalyn Yalow
D. George Snell, Jean Dausset, Baruj Benaceraf
E. Niels Jerne

A

E. Niels Jerne

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Q

Radioimmunoassay

A. MacFarlane Burnet, Peter Medewar
B. Gerald Edelman, Rodney Porter
C. Rosalyn Yalow
D. George Snell, Jean Dausset, Baruj Benaceraf
E. Niels Jerne

A

C. Rosalyn Yalow

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Q

Major Histocompatibility complex

A. MacFarlane Burnet, Peter Medewar
B. Gerald Edelman, Rodney Porter
C. Rosalyn Yalow
D. George Snell, Jean Dausset, Baruj Benaceraf
E. Niels Jerne

A

D. George Snell, Jean Dausset, Baruj Benaceraf

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Q

Transplantation

A. Georges Koehler, Cesar Milstein
B. Susumu Tonegawa
C. Edward Donnall Thomas, Joseph Murray
D. Peter Doherty, Rolf Zinkernagel
E. Francois Barre-Sinoussi, Luc Montagnier

A

C. Edward Donnall Thomas, Joseph Murray

Q

Monoclonal antibody

A. Georges Koehler, Cesar Milstein
B. Susumu Tonegawa
C. Edward Donnall Thomas, Joseph Murray
D. Peter Doherty, Rolf Zinkernagel
E. Francois Barre-Sinoussi, Luc Montagnier

A

A. Georges Koehler, Cesar Milstein

Q

Antibody Diversity

A. Georges Koehler, Cesar Milstein
B. Susumu Tonegawa
C. Edward Donnall Thomas, Joseph Murray
D. Peter Doherty, Rolf Zinkernagel
E. Francois Barre-Sinoussi, Luc Montagnier

A

B. Susumu Tonegawa

Q

Human immunodeficiency virus

A. Georges Koehler, Cesar Milstein
B. Susumu Tonegawa
C. Edward Donnall Thomas, Joseph Murray
D. Peter Doherty, Rolf Zinkernagel
E. Francois Barre-Sinoussi, Luc Montagnier

A

E. Francois Barre-Sinoussi, Luc Montagnier

Q

Cytotoxic T cell recognition of virally infected cells

A. Georges Koehler, Cesar Milstein
B. Susumu Tonegawa
C. Edward Donnall Thomas, Joseph Murray
D. Peter Doherty, Rolf Zinkernagel
E. Francois Barre-Sinoussi, Luc Montagnier

A

D. Peter Doherty, Rolf Zinkernagel

Q

First Responder to INFECTION, PHAGOCYTOSIS

A. EOSINOPHILS
B. NEUTROPHILS
C. BASOPHILS
D. MAST CELLS

A

B. Neutrophils

Q

PHAGOCYTOSIS; kill INTRACELLULAR PARASITES, TUMORCIDAL activity; antigen presentation to T AND B CELLS

A. EOSINOPHILS
B. NEUTROPHILS
C. MONOCYTES
D. MAST CELLS

A

C. MONOCYTES

Q

KILL PARASITES, neutralize BASOPHILS and MAST CELL PRODUCTS, regulate Mast Cells

A. EOSINOPHILS
B. NEUTROPHILS
C. LYMPHOCYTES
D. MONOCYTES

A

A. EOSINOPHILS

Q

Antigen presenting to T and B cells; enhancement and suppression of the adaptive immune response

A. EOSINOPHILS
B. NEUTROPHILS
C. BASOPHILS
D. MAST CELLS

A

D. Mast Cells

Induce and maintain ALLERGIC REACTIONS, stimulate production of IgE A. DENDRITIC CELL B. LYMPHOCYTES C. BASOPHILS D. MAST CELLS

C. Basophils

MOST POTENT PHAGOCYTIC CELL, Most effective at antigen presentation A. DENDRITIC CELL B. LYMPHOCYTES C. BASOPHILS D. MAST CELLS

A. DENDRITIC CELL

Subtypes are T cells, B cells and NK cells A. DENDRITIC CELL B. LYMPHOCYTES C. BASOPHILS D. MAST CELLS

B. LYMPHOCYTES * T Cells: Produces Cytokines B Cells: Produce antibody in Adaptive Immune Response NK Cells: Involved in innate immunity

PRIMARY LYMPHOID ORGANS: A. SPLEEN B. LYMPH NODES C. BM D. MALT

C. BM * PRIMARY LYMPHOID ORGANS: BM THYMUS

Produces hematopoietic stem cells; maturation of B cells and NK cells A. BM B. Thymus

A. BM

Maturation of T Cells A. BM B. Thymus

B. Thymus

•Developed in THYMUS •60-80% Circulating pool in Blood • ADAPTIVE IMMUNITY • end product of activation are CYTOKINES • ANTIGENS INCLUDE : CD2, CD3, CD4 CD8 A. B cells B. T cells C. NK cells

B. T Cells

•Developed in BM •10-15% or 20-35% Circulating in Lymphocyte pool in the Blood •ADAPTIVE IMMUNITY •end product of activation is ANTIBODY •ANTIGENS INCLUDE CD19, CD20, CD21, SURFACE ANTIBODY A. B cells B. T cells C. NK cells

A. B Cells

•Developed in BM •5-15% Circulating in Lymphocyte pool in the Blood •INNATE IMMUNITY •ANTIGENS INCLUDE CD16, CD56 A. B cells B. T cells C. NK cells

C. NK Cells

Lacks CD4 & CD8 A. DOUBLE NEGATIVE THYMOCYTES B. DOUBLE POSITIVE THYMOCYTES

A. DOUBLE NEGATIVE THYMOCYTES

Express both CD4 CD8 A. DOUBLE NEGATIVE THYMOCYTES B. DOUBLE POSITIVE THYMOCYTES

B. DOUBLE POSITIVE THYMOCYTES

Either CD4 OR CD8, MIGRATE TO MEDULLA A. MATURE T CELLS B. ACTIVATED T CELLS C. SENSITIZED T CELLS

A. MATURE T CELLS

Activated T lymphocytes express receptors for IL-2 A. MATURE T CELLS B. ACTIVATED T CELLS C. SENSITIZED T CELLS

B. ACTIVATED T CELLS

Differentiate into functionally active small lymphocytes that produces CYTOKINES A. MATURE T CELLS B. ACTIVATED T CELLS C. SENSITIZED T CELLS

C. SENSITIZED T CELLS