ISBB Flashcards
Cross immunity
A. Edward Jenner
B. Louis Pasteur
A. Edward Jenner
*Cowpox, small pox
Father of Immunology/ First attenuated vaccine
A. Edward Jenner
B. Louis Pasteur
B. Louis Pasteur
Discovey of T cell receptor gene
A. 1798
B. 1880
C. 1901
D. 1984
D. 1984
- By Tak Wah Mak, Mark Davis
Serum antitoxin
A. Robert Koch
B. Emil von Behring
B. Emil von Behring
Cellular immunity in TB:
A. Robert Koch
B. Elie Metchnikoff
C. Charles Ricket
D. Jules Bordet
E. Karl Landsteiner
F. Paul Ehrlich
A. Robert Koch
Complement:
A. Robert Koch
B. Elie Metchnikoff
C. Charles Ricket
D. Jules Bordet
E. Karl Landsteiner
F. Paul Ehrlich
D. Jules Bordet
Anaphylaxis:
A. Robert Koch
B. Elie Metchnikoff
C. Charles Ricket
D. Jules Bordet
E. Karl Landsteiner
F. Paul Ehrlich
C. Charles Ricket
Human Blood Group antigens:
A. Robert Koch
B. Elie Metchnikoff
C. Charles Ricket
D. Jules Bordet
E. Karl Landsteiner
F. Paul Ehrlich
E. Karl Landsteiner
Immunity:
A. Robert Koch
B. Elie Metchnikoff
C. Charles Ricket
D. Jules Bordet
E. Karl Landsteiner
F. Paul Ehrlich
F. Paul Ehrlich
Phagocytosis:
A. Robert Koch
B. Elie Metchnikoff
C. Charles Ricket
D. Jules Bordet
E. Karl Landsteiner
F. Paul Ehrlich
B. Elie Metchnikoff
Structure of antibodies:
A. MacFarlane Burnet, Peter Medewar
B. Gerald Edelman, Rodney Porter
C. Rosalyn Yalow
D. George Snell, Jean Dausset, Baruj Benaceraf
E. Niels Jerne
B. Gerald Edelman, Rodney Porter
Discovery of Immunologic tolerance
A. MacFarlane Burnet, Peter Medewar
B. Gerald Edelman, Rodney Porter
C. Rosalyn Yalow
D. George Snell, Jean Dausset, Baruj Benaceraf
E. Niels Jerne
A. MacFarlane Burnet, Peter Medewar
Immunoregulation
A. MacFarlane Burnet, Peter Medewar
B. Gerald Edelman, Rodney Porter
C. Rosalyn Yalow
D. George Snell, Jean Dausset, Baruj Benaceraf
E. Niels Jerne
E. Niels Jerne
Radioimmunoassay
A. MacFarlane Burnet, Peter Medewar
B. Gerald Edelman, Rodney Porter
C. Rosalyn Yalow
D. George Snell, Jean Dausset, Baruj Benaceraf
E. Niels Jerne
C. Rosalyn Yalow
Major Histocompatibility complex
A. MacFarlane Burnet, Peter Medewar
B. Gerald Edelman, Rodney Porter
C. Rosalyn Yalow
D. George Snell, Jean Dausset, Baruj Benaceraf
E. Niels Jerne
D. George Snell, Jean Dausset, Baruj Benaceraf
Transplantation
A. Georges Koehler, Cesar Milstein
B. Susumu Tonegawa
C. Edward Donnall Thomas, Joseph Murray
D. Peter Doherty, Rolf Zinkernagel
E. Francois Barre-Sinoussi, Luc Montagnier
C. Edward Donnall Thomas, Joseph Murray
Monoclonal antibody
A. Georges Koehler, Cesar Milstein
B. Susumu Tonegawa
C. Edward Donnall Thomas, Joseph Murray
D. Peter Doherty, Rolf Zinkernagel
E. Francois Barre-Sinoussi, Luc Montagnier
A. Georges Koehler, Cesar Milstein
Antibody Diversity
A. Georges Koehler, Cesar Milstein
B. Susumu Tonegawa
C. Edward Donnall Thomas, Joseph Murray
D. Peter Doherty, Rolf Zinkernagel
E. Francois Barre-Sinoussi, Luc Montagnier
B. Susumu Tonegawa
Human immunodeficiency virus
A. Georges Koehler, Cesar Milstein
B. Susumu Tonegawa
C. Edward Donnall Thomas, Joseph Murray
D. Peter Doherty, Rolf Zinkernagel
E. Francois Barre-Sinoussi, Luc Montagnier
E. Francois Barre-Sinoussi, Luc Montagnier
Cytotoxic T cell recognition of virally infected cells
A. Georges Koehler, Cesar Milstein
B. Susumu Tonegawa
C. Edward Donnall Thomas, Joseph Murray
D. Peter Doherty, Rolf Zinkernagel
E. Francois Barre-Sinoussi, Luc Montagnier
D. Peter Doherty, Rolf Zinkernagel
First Responder to INFECTION, PHAGOCYTOSIS
A. EOSINOPHILS
B. NEUTROPHILS
C. BASOPHILS
D. MAST CELLS
B. Neutrophils
PHAGOCYTOSIS; kill INTRACELLULAR PARASITES, TUMORCIDAL activity; antigen presentation to T AND B CELLS
A. EOSINOPHILS
B. NEUTROPHILS
C. MONOCYTES
D. MAST CELLS
C. MONOCYTES
KILL PARASITES, neutralize BASOPHILS and MAST CELL PRODUCTS, regulate Mast Cells
A. EOSINOPHILS
B. NEUTROPHILS
C. LYMPHOCYTES
D. MONOCYTES
A. EOSINOPHILS
Antigen presenting to T and B cells; enhancement and suppression of the adaptive immune response
A. EOSINOPHILS
B. NEUTROPHILS
C. BASOPHILS
D. MAST CELLS
D. Mast Cells
Induce and maintain ALLERGIC REACTIONS, stimulate production of IgE
A. DENDRITIC CELL
B. LYMPHOCYTES
C. BASOPHILS
D. MAST CELLS
C. Basophils
MOST POTENT PHAGOCYTIC CELL, Most effective at antigen presentation
A. DENDRITIC CELL
B. LYMPHOCYTES
C. BASOPHILS
D. MAST CELLS
A. DENDRITIC CELL
Subtypes are T cells, B cells and NK cells
A. DENDRITIC CELL
B. LYMPHOCYTES
C. BASOPHILS
D. MAST CELLS
B. LYMPHOCYTES
- T Cells: Produces Cytokines
B Cells: Produce antibody in Adaptive Immune Response
NK Cells: Involved in innate immunity
PRIMARY LYMPHOID ORGANS:
A. SPLEEN
B. LYMPH NODES
C. BM
D. MALT
C. BM
- PRIMARY LYMPHOID ORGANS:
BM
THYMUS
Produces hematopoietic stem cells; maturation of B cells and NK cells
A. BM
B. Thymus
A. BM
Maturation of T Cells
A. BM
B. Thymus
B. Thymus
•Developed in THYMUS
•60-80% Circulating pool in Blood
• ADAPTIVE IMMUNITY
• end product of activation are CYTOKINES
• ANTIGENS INCLUDE : CD2, CD3, CD4 CD8
A. B cells
B. T cells
C. NK cells
B. T Cells
•Developed in BM
•10-15% or 20-35% Circulating in Lymphocyte pool in the Blood
•ADAPTIVE IMMUNITY
•end product of activation is ANTIBODY
•ANTIGENS INCLUDE CD19, CD20, CD21, SURFACE ANTIBODY
A. B cells
B. T cells
C. NK cells
A. B Cells
•Developed in BM
•5-15% Circulating in Lymphocyte pool in the Blood
•INNATE IMMUNITY
•ANTIGENS INCLUDE CD16, CD56
A. B cells
B. T cells
C. NK cells
C. NK Cells
Lacks CD4 & CD8
A. DOUBLE NEGATIVE THYMOCYTES
B. DOUBLE POSITIVE THYMOCYTES
A. DOUBLE NEGATIVE THYMOCYTES
Express both CD4 CD8
A. DOUBLE NEGATIVE THYMOCYTES
B. DOUBLE POSITIVE THYMOCYTES
B. DOUBLE POSITIVE THYMOCYTES
Either CD4 OR CD8, MIGRATE TO MEDULLA
A. MATURE T CELLS
B. ACTIVATED T CELLS
C. SENSITIZED T CELLS
A. MATURE T CELLS
Activated T lymphocytes express receptors for IL-2
A. MATURE T CELLS
B. ACTIVATED T CELLS
C. SENSITIZED T CELLS
B. ACTIVATED T CELLS
Differentiate into functionally active small lymphocytes that produces CYTOKINES
A. MATURE T CELLS
B. ACTIVATED T CELLS
C. SENSITIZED T CELLS
C. SENSITIZED T CELLS
