Integumentary System Flashcards
Functions of the integumentary system
protection
defense
sensation
secretion of pre-vitamin D
thermoregulation (sweat)
blood resevoir
excretion of electrolytes
what is another term for subcutaneous fat layer
hypodermis
is the hypodermis a part of the skin
no
What is the majoirty of epidermal cells
keratinocytes- make keratin
what is meant by healthy mitotic state in epidermis
the keratinocytes live 25-45 days
get replaced
what are melanocytes and where are they
make melanin
located on basal layer of epidermis
what do melanocytes do
secrete melanin granules that percolate upward
absorb UV radiation
what do merkel cells do
sensory receptor (only one in epidermis)
where are merkel cells located
basal layer of epidermis
what are Langerhan’s cells
dendritic cells
macrophages in epidermis
what are the epidermal layers in order from top to bottom
stratum corneum
stratum lucidum (if thick skin)
stratum granulosum
stratum spinosum
stratum basale
what are the characteristics of the stratum corneum
flattened, thick keratinized cells
what does stratum corneum do
natural exfoliation
dead cells dump keratin
what are the characteristics of stratum lucidum
only in thick/hairless skin
shows bright pink above granulosum
what are the characteristics of stratum granulosum
dark landmark layer
cells begin to flatten, lose their organelles, their plasma membrane thickens
purple granules
characteristics of stratum spinosum
point looking cells with spindle fibers
major layer of live cells
resists tension
characteristics of stratum basale
basement layer
constant mitosis here
dark blobs on slide
name what can cause cancer through the integumentary system
UV radiation
what are the types of radiation and what do they do
UVA- skin aging
UVB- skin cancer; sunburns
explain squamous cell carcinoma
develops in stratum spinosa
there is some kind of failure of apoptosis leaving cells around too long to get exposed to environment
explain basal cell carcinoma
abnormal growth of basal cells
usually dont metastisize for a long time
explain melanoma
can be in tissue never exposed to sun
cancer of melanocytes
systemic reaction to radiation
very malicious; often metastisizes to other organs
What comprises the dermis
fibroblasts
fibers
mast cells
WBCs
what are the two layers of the dermis
papillary
reticular
what is the papillary layer of the dermis made of
areolar connective tissue
describe the papillary layer of dermis
very thin layer
vary vascularized
has meissner’s corpuscles papilla
dermal ridges form epidermal ridges which include fingerprints
what is the reticular layer of the dermis made of
dense irregular CT
what are cleavage lines
affect how incision gapes
what are flexure lines
folds around joints
what are the types of sudoriferous (non specified sweat gland)
eccrine
apocrine
ceruminous
mammary
what are sudoriferous sweat glands made of
simple cuboidal ET
what mode of secretion do all sudoriferous sweat glands use
merocrine
describe eccrine sweat gland
most common
has own pore on surface of skin
used for thermoregulation and keeps microbes at bay
describe apocrine sweat gland
dont secrete until puberty
axilla and anogenital regions
attached to hair follicles/empties into follicle duct
made of a lot fo lipids and keratinocytes
acne when clogged
what is ceruminous sweat gland
earwax
what is mammary sweat gland
specialized
describe sebaceous glands
secrete sebum with the help of arrector pilli muscle
found everywhere but palms and soles
relatively inactive before puberty
how many nerve endings in integumentary system
numerous
what are merkle cells
light touch receptor where hair is
what are meissner’s corpuscles
light touch in hairless areas
located in dermal papilla
what is the arrector pili
muscle
hair stands on end; connected to hair follicle
helps to secrete sebum into follicle from sebaceous glands
what are pancinian corpuscles
intial pressure sensation and sensation of vibration
deep touch