INSULIN Flashcards

1
Q

1st action of insulin:

A

First, it promotes uptake of glucose by target cells and increases glycogen synthesis

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2
Q

2nd action of insulin:

A

2nd, it prevents fat and glycogen breakdown

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3
Q

3rd action of insulin:

A

3rd, it inhibits gluconeogenesis and increases protein synthesis

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4
Q

Glut 1:

A

Present in all tissues and does not require the actions of insulin

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5
Q

Glut 2:

A

Major transporter for glucose into beta and liver cells

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6
Q

Glut 3:

A

Major transporter for glucose in neutrons and is highly expressed in brain. Does not require insulin for its action

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7
Q

Glut 4:

A

Insulin dependent glucose transporter for skeletal and adipose tissue
- stimulated by insular to move from its inactive site to the cell membrane where it facilitates glucose entry

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8
Q

All 4 glut’s:

A

— Important in the transport ot glucose in to cells of the ns and facilitates glucose movement across blood brain barrier
_ all these glucose transporters move glucose across the cell membrane at a faster rate than would occur with diffusion alone

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