GLUCOSE METABOLISM Flashcards

1
Q

What is glucose?

A

6 carbon molecule and serves as an efficient fuel source

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2
Q

What is glucose broken down in to?

A

Carbon dioxide and water an then metabolized in the presence of oxygen

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3
Q

What systems solely rely on glucose as their source of fuel?

A

Brain and nervous system
- other tissues organ systems can use other non carb fuel (fatty acids and ketones)

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4
Q

Can the brain synthesize or store glucose?

A

NO
- cannot store more than a few minutes worth of glucose supply

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5
Q

Fasting blood glucose is tightly regulated between what mmol/L?

A

4.4-5.0

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6
Q

Insulin is secreted by what? And where?

A

Beta cells. In pancreas in response to rising blood glucose

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7
Q

After a meal, 2/3 of glucose is stored where? And as what?

A

Liver. Glycogen

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8
Q

How does the liver release glucose?

A

By breaking down glycogen in a process called glycogenolysis to maintain normoglycemia

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9
Q

Once liver and skeletal muscles saturated with glycogen, what happens to the extra glucose?

A

Converted into fatty acids by the liver - stored as triglycerides in adipose tissue (tat)

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10
Q

What is the process of gluconeogenesis?

A

Liver synthesizes glucose from non carb sources

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