Innate immunity Flashcards
Pathogen-
Examples
-any organism that can cause disease
eg. bacteria, virus, parasite, fungi
Innate/ non specific defence
-large range of responses
-first and second line
-no memory
Adaptive/ specific defence
-immunological memory
-recognise and bind to specific antigen
First line of defence
-skin
-nasal hairs
-stomach acid
-mucous membrane
-cilia
-urinary tract
Second line of defence
-inflammatory response
-phagocytosis
WBCs
Leukocytes
-phagocytes, monocytes, macrophages, dendritic cells
Cells of the innate immune system
-mast cell
-granulocytes
-phagocytes- neutrophil, macrophage, dendritic cell
-natural killer cell
Cells of the adaptive immune system
B cells
-memory and plasma
T cells
-helper and cytotoxic
Phagocytosis
-WBC receptors recognise pathogen as foreign when pathogen interacts with phagocyte
-phagocyte engulfs pathogen
-lysosome digests pathogen
-pathogen breaks down into proteins and other molecules
-major histocompatibility complex binds to the membrane of the phagocyte to form an antigen presenting cell