Acid base balance and buffers Flashcards

1
Q

Normal pH range of blood

A

7.35-7.45

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2
Q

Survival range of pH of blood

A

6.8-8.0

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3
Q

Salts

A

-produced from a reaction between an acid and a base
-hydrogen from acid replaced by cation in the base
HCl + NaOH-> NaCl + H2O

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4
Q

Buffer

A

-substance that prevents sharp changes in pH
-work by accepting or releasing H+ ions
eg. bicarbonate, phosphate, proteins (haemoglobin)

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5
Q

3 systems that help maintain blood pH

A

-buffer system
-respiratory system
-renal system

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6
Q

Respiratory acidosis (low pH)
what is it, signs, causes

A

Failure of ventilation so CO2 accumulates, decreasing pH
Signs
-hypoventilation
-rapid, shallow respirations
-decrease BP
-headache
-hyperkalemia- high K+ levels
-dizziness
-muscle weakness
Causes
-drug overdose
-anesthesia
-COPD- chronic obstructive pulmonary disease
-pneumonia

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7
Q

Respiratory alkalosis
what is it, signs, causes

A

pH is above 7.45
Signs
-seizures
-rapid breathing
-hyperventilation
-tachycardia
-confusion
-dizzy
-nausea
Causes
-hyperventilation- anxiety

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8
Q

Metabolic acidosis
what is it, signs, causes

A

-
Signs
-headache
-decrease BP
-muscle twitching
-changes in LOC

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9
Q

Bicarbonate buffer system

A

H2CO3 -> HCO3- + H+
pH decrease- more H2CO3 formed, equilibrium shifts left. H2CO3 breaks down to CO2 and H2O to be exhaled
pH increase- H+ react with OH- to form water, pushes equilibrium to the right

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9
Q

Metabolic alkalosis
Signs

A

-tachycardia
-confusion
-nausea

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