inhibitory synapses Flashcards
How do sodium ions diffuse into a neurone
Neurotransmitter binding causes sodium ion channel proteins to open
What happens when the sodium ions enter the neurone
The cell becomes depolarised (action potential has been transferred to next neurone)
What is it called when next neurone becomes depolarised (transferring of the action potential
The excitatory postsynaptic potential (EPSP)
What is an IPSP
Inhibitory post synaptic potential (discourages an action potential by bring membrane potential down decreases chance of depolarisation)
What does an IPSP do to the post synaptic neurone
Hyperpolarises it rather than depolarising it
What happens as a result of IPSP
It makes it much harder for an action potential to be initiated in the cell
What happens if an EPSP follows an IPSP
The membrane potential will stay roughly at rest as the 2 cancel each other out
How is an IPSP initiated
With the release of neurotransmitter from the pre-synaptic neurone
What do the neurotransmitters released due to IPSP do
Bind to receptors on post-synaptic membrane
What are the 2 types of receptors that neurotransmitters released bind to due to IPSP
Chloride ion channels
Potassium ion channels
What do chloride ion and potassium ion channels do in response to neurotransmitter binding
Open
What happens when chloride ion channels open
As their is a low concentration inside the cell of (-) chloride ions they rush into the cell. Hyper polarises the cell.
What happens when pottassium channels open
The concentration of potassium ions (+) inside the cell is very high so they leave the cell further hyper polarising the cell.
