link reaction Flashcards
What does the link reaction involve
Conversion of pyruvate to a 2 carbon acetyl group
Where does the link reaction take place
Mitochondrial matrix
What is removed from pyruvate
A carboxyl group and hydrogen atoms
What is it called when a carboxyl group is removed from something
Decarboxylation
What is it called when hydrogen atoms are removed
oxidation or dehydrogenation
What is the decarboxylation and dehydrogenation of pyruvate catalysed by
Pyruvate dehydrogenase
What is produced as result of the decarboxylation of the carboxyl group
Carbon dioxide
What happens to the hydrogen atoms dehydrogenated from pyruvate
They are accepted by oxidised NAD producing reduced NAD
The decarboxylation and dehydrogenation of pyruvate results in the formation of
an acetyl group (2C)
What happens to the acetyl produced by the decarboxylation and dehydrogenation of the pyruvate
It combines with a molecule of coenzyme A to form acetyl coenzyme A
What does link reaction result in the production of
Carbon dioxide, reduced NAD, and acetyl coenzyme A
