Infectious Diseases II Flashcards

1
Q

Infuse cefazolin or cefuroxime ___ min before start of surgery

A

60 min

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2
Q

If a quinolone or Vanc are used, start the infusion ___ min before start of surgery

A

120 min

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3
Q

Give additional dose/s if surgery is >__ hours, or with major blood loss

A

3-4h

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4
Q

Post-surgery, abc are not used; d/c within __ hrs

A

24h

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5
Q

This abx is preferred for most surgeries to prevent MSSA and streptococci infections; what is an alternative if a B-lactam allergy?

A

Cefazolin, a first generation cephalosporin; or a second-gen ceph: cefuroxime

Alt: clindamycin

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6
Q

In colorectal surgeries, the prophylactic regimen needs to cover skin flora + broad gram (-) and anaerobic organisms found in the gut. Recommended antibiotics:

A

Cefotetan, cefoxitin, ampicillin/sulbactam, ertapenem, or

metronidazole + (cefazolin or ceftriaxone)

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7
Q

Colorectal surgery prophylaxis, if beta-lactam allergy present

A

Clindamycin + (AG, quinolone, or Aztreonam) or

metronidazole + (AG or quinolone)

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8
Q

Cardiac or vascular surgery prophylaxis

A

Cefazolin or cefuroxime

BL allergy: vancomycin or clindamycin

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9
Q

Hip fracture of total joint replacement surgery prophylaxis

A

Cefazolin

BL allergy: vancomycin or clindamycin

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10
Q

Meningitis- this bacterium is prevalent in neonates, age >50y, and immunocompromised groups and requires additional treatment with ampicillin

A

Listeria monocytogenes

Common bacteria: S. pneumoniae, Neisseria meningitides, and H. influenzae

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11
Q
Acute bacterial meningitis tx (CA)-
Antibiotic durations:
- N. meningitidis:
- H. influenzae:
- S. Pneumoniae:
- Listeria Monocytogenes:
A

Antibiotic durations:

  • N. meningitidis: 7 days
  • H. influenzae: 7 days
  • S. Pneumoniae: 10-14 days
  • Listeria Monocytogenes: 21 days
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12
Q

Acute bacterial meningitis tx (CA)-

To prevent neurological complications, _____ can be given prior to or with the first antibiotic dose

A

20 mins prior to dose, Dexamethasone 0.15mg/kg IV Q6H x 4 days

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13
Q

Treatment for acute Otitis media in children

A

amoxicillin 80-90mg/kg/day BID OR amox/clav. 90mg/kg/day + 6.4mg/kg/day BID.

If vomiting: ceftriaxone 50mg/kg IM or IV x 1-3days

The high amoxicillin doses are needed to cover most strains of S. pneumoniae

NOTES:
With amox/clav, the formulation with the LEAST amt of clavulanate should be used to dec the risk of diarrhea. 14:1 ratio –> amoxicillin 600mg and clavulanate 42.9mg/5mL

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14
Q

Acute otitis media treatment in kids: when to consider observation?

How many days? & Temp < ??

Age 6-23 months sx?
Age >2y sx?

A

try observation for 2-3 days if mild ear pain and temp <102.2F and:

  • age 6-23 months: sx in one ear only
  • age >2y: sx in one or both ears
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15
Q

Pharyngitis treatment

A

Penicilllin,

amoxicillin

or 1st/2nd gen cephalosporin (cefazolin, cefuroxime, cefotetan) x 10 days

azithromycin x 5 days

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16
Q

Sinusitis treatment

A

First line: amox/clav
Second line or failure of first: oral 2nd/3rd gen cephalosporin +clindamycin, doxycycline, or a respiratory quinolone (GML)

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17
Q

Influenza treatment

A

Oseltamivir x 5 days
Baloxavir x 1 dose
Zanamivir inhalation x 5 days

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18
Q

Acute bronchitis treatment

A

Supportive; abx are not recommended unless pneumonia is present.

The exception is Bordetella pertussis (macrolide - azithromycin, clarithromycin or Bactrim)

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19
Q

Acute bacterial exacerbation of chronic bronchitis can be referred to as a

A

COPD exacerbation

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20
Q

COPD exacerbation treatment

A

Supportive treatment (O2, short-acting bronchodilators, IV or PO steroids)

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21
Q

When should abx be given in a COPD exacerbation? (tx is for 5-7 days)

A
  • All of the following: INC dyspnea, INC sputum volume, INC sputum purulence
  • INC sputum purulence + 1 additional sx
  • mechanically ventilated
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22
Q

What are the preferred antibiotics in a COPD exacerbation?

A

Amoxicillin/Clavulanate
Azithromycin
Doxycycline

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23
Q

A chest X-ray is the gold standard test for the diagnosis of _____ and will have infiltrates, opacities or consolidations

A

Community-acquired pneumonia

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24
Q

Most bacterial CAP cases are caused by

A

S. pneumoniae, H. influenzae, M. Pneumoniae, and possibly C. Pneumoniae

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25
Q

What is the duration for treatment for CAP?

A

5-7 days

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26
Q

Outpatient treatment of CAP requires an assessment of pt comorbidities and risk factors for drug-resistant pathogens. Patients with comorbidities or immunosuppression require:

A

broader coverage of possible drug-resistant S. pneumoniae

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27
Q

Step 1 of the outpatient CAP assessment

A

Look for comorbities (CHF, lung, liver, or renal disease, diabetes, alcoholism, cancer, or asplenia)

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28
Q

Step 2 of the outpatient CAP assessment

A

Check for MRSA or P.aerugenisoa risk factors, receipt of parenteral abx

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29
Q

Recommended empiric regimen for CAP if patient does not have any comorbidities

A

Amoxicillin high-dose (1 gram TID), or

Doxycycline, or

Macrolide (azithromycin or clarithromycin) if local pneumococcal resistance is <25%

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30
Q

Recommended empiric regimen for CAP if patient does have comorbidities

A

Beta-lactam + macrolide or doxycycline

  - Amox/Clav or (cefpodoxime, cefdinir, cefuroxime) plus
   - macrolide or doxycycline

Respiratory quinolone mono therapy (GML)

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31
Q

Inpatient CAP treatment: selection of an empiric regimen is based on:

A

severity of illness and often includes IV abx initially

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32
Q

Inpatient CAP tx: non-severe/ non-ICU care

A
  • Beta-lactam + macrolide or doxycycline
    • preferred beta-lactams: ceftriaxone, cefotaxime, ceftaroline, or amp/sulbactam
  • Respiratory quinolone monotherapy
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33
Q

Inpatient CAP tx: severe/ICU care

A

Beta-lactam + macrolide

Beta-lactam + respiratory quinolone (do NOT use quinolone as mono therapy)

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34
Q

Inpatient CAP tx: concern for MRSA.

Add coverage with:

A

add coverage with vancomycin or linezolid

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35
Q

Inpatient CAP tx: concern for pseudomonas

Add coverage with:

A

add coverage with pip/tazo, cefepime, merwpenam, Aztreonam, ceftazidime

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36
Q

Hospital-acquired pneumonia (HAP) has an onset of >___ hours after hospital admission

A

> 48 hours – HAP is the leading infectious cause of death in ICU patients

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37
Q

Ventilator-associated pneumonia (VAP) occurs > ___ hours after the start of mechanical ventilation

A

> 48 hours;
rate of VAP can be reduced by:
-proper handwashing
- elevating the head of the bed >30 degrees
- weaning off the ventilator ASAP
- removing NG tubes
- D/C unnecessary stress ulcer prophylaxis

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38
Q

Nosocomial pathogens are common in these infectious situations; the risk for MRSA and MDR gram-negative rods, including P. aeruginosa, acinetobacter spp, enterobacter spp, E.coli and Klebsiella spp is increased in selected cases

A

HAP & VAP

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39
Q

Empiric Regimen: HAP/VAP

Patient has a low risk for MRSA or MDR pathogens

A

Choose 1 abx:
Cefepime or
pip/tazo

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40
Q

Empiric Regimen: HAP/VAP

Patient has a risk for MRSA, but low risk of MDR pathogens

A

Choose 2 abx:

  • cefepime + vancomycin

- Meropenem + linezolid

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41
Q

Empiric Regimen: HAP/VAP

Patient has a risk for both MRSA and MDR pathogens (IV abx within the past 90 days)

A

Choose 3 abx:

  • pip/tazo + ciprofloxacin + vancomycin

- cefepime + gentamicin + linezolid

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42
Q
  • Positive MRSA nasal swab
  • high prevalence of resistant pathogen noted in hospital unit
  • IV antibiotics use within the past 90 days

are all high risk of

A

MRSA or MDR pathogens

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43
Q

List antibiotics for pseudomonas

A

PSEUDOMONAS –

Pip/tazo
Cefepime, ceftazidime, or ceftolozane/tazo

Quinolones: Levofloxacin or ciprofloxacin

Carbapenems: Imipenem/cilastatin or meropenem

AG: Tobramycin, gentamicin or amikacin (not mono)

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44
Q

Antibiotics for MRSA

A

Vancomycin or linezolid

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45
Q

Active pulmonary TB is transmitted by

A

aerosolized droplets (sneezing, coughing, talking) & highly contagious

Presents with cough/hemoptysis, purulent sputum, fever, and night sweats

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46
Q

A false positive TB (TST) test can occur in those who have received what vaccine?

A

Bacille Calmette-Gurein (BCG) vaccine

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47
Q

Latent TB treatment: shorter regimens are preferred (3-4 months) due to higher completion rates and less risk of

A

hepatotoxicity

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48
Q

Latent TB treatment: this regimen is once weekly x 12 weeks via directly observed therapy or self-administered

A

INH and rifapentine once weekly x 12 weeks

Strongly recommended in adults, children >2y, and HIV patients.

NOT for pregnant women.

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49
Q

Latent TB treatment: This regimen is a preferred regimen in children of all ages and HIV-negative adults

A

Rifampin 600mg daily x 4 months

Drug interactions :(

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50
Q

Latent TB treatment: this regimen is daily x 3 months and can be used in adults, children of all ages, and HIV+ patients

A

Isoniazid + rifampin daily x 3 months

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51
Q

Latent TB treatment: an alternate regimen-

for HIV- or HIV+ adults and children of all ages, treatment of choice for pregnant women.

A

Isoniazid 300mg PO daily x 6 months

Isoniazid 300mg PO daily x 9 months (TOC preg)

52
Q

Active TB must be confirmed with a

A

sputum culture

M. tuberculosis is an acid-fast bacilli and can be detected using an AFB stain, but SLOW, can take up tp 6 weeks

53
Q

Active TB treatment: is divided into 2 phases (intensive and continuation).
To avoid resistance, the preferred intensive regimen consists of 4 drugs (2 months):

A

Rifampin, isoniazid, pyrazinamide, and ethambutol; daily or 5x/week x 2 months (“RIPE” therapy)

54
Q

Active TB treatment: is divided into 2 phases (intensive and continuation).
In the continuation phase (4 months), treatment is scaled back to 2 drugs:

A

rifampin and isoniazid daily, 5x per week or 3x per week

based on the drug susceptibility of the isolate.

Can be extended to 7 months if sputum culture remains positive after 2 months of treatment, or if intensive phase treatment did not include pyrazinamide

55
Q

MDR-TB treatment: preferred drugs include

A

quinolone (moxi or levo), or injectables (streptomycin, amikacin, or kanamycin) x 24 months

56
Q

Extremely MDR-TB treatment:

A

bedaquiline (Sirturo), boxed warnings for QT prolongation and an increased risk of death

Pretomanid + bedaquiline + linezolid, but hepatoxocity, peripheral neuropathy. optic neuropathy, myelosuppresion, QT prolongation

57
Q
This TB drug can:
increase LFTs,
hemolytic anemia (+Coombs test)
Orange-red discoloration of body secretions
Flu-like sx
A

Rifampin; take on empty stomach

MANY drug interactions, can be replaced with rifabutin in some cases (HIV protease inhibitors)

58
Q

Rifadin

A

Rifampin

59
Q

Rifamate

A

Rifampin + isoniazid

60
Q

Rifater

A

Rifampin + isoniazid + pyrazinamide

61
Q

Isoniazid is taken with ____ daily to decrease the risk of INH-associated peripheral neuropathy

A

pyridoxine 25-50mg PO daily

62
Q

This TB drug has a boxed warning for severe and fatal hepatitis
Can also cause DILE, hemolytic anemia

A

Isoniazid

63
Q

This TB drug is contraindicated in acute gout; can increase LFTs, and can cause optic neuritis (dose-related), hallucinations, confusion

A

Ethambutol

64
Q

Myambutol

A

Ethambutol

65
Q

Noteable interactions of Rifampin include:

A

protease inhibitors (substitute with rifabutin)
Warfarin (very large dec in INR)
OC (dec efficacy)

66
Q

DO NOT USE rifampin with

A

apixiban, rivaroxaban, edoxaban, or dabigatran

67
Q

Infective endocarditis is diagnosed using what criteria?

A

Modified Duke Criteria:

- ECG to visualize the vegetation and positive blood cultures

68
Q

The three most common species of organisms that cause IE are:

A

staphylococci, streptococci, and Enterococci

69
Q

IE Empiric treatment often includes:

A

Vanc and ceftriaxone

70
Q

This antibiotic is added to the IE regimen for synergy when the infection is more difficult to eradicate (prosthetic valve infections)

A

Gentamicin, peak levels of 3-4mcg/mL and trough levels <1mcg/mL x 2-6 weeks

71
Q

IE Abx treatment duration

A

4-6 weeks of IV antibiotic treatment is required

72
Q

IE: some bacteria can form a biofilm, especially on prosthetic valves. What abx is used?

A

Rifampin is used in cases of staphylococcal

73
Q

IE treatment-
Organism: Viridans group Streptococci
Preferred Abx regimen:

A

Penicillin or ceftriaxone (+/- gentamicin)

If beta-lactam allergy: use vancomycin monotherapy

74
Q

IE treatment-
Organism: Staphylococcal (MSSA)
Preferred Abx regimen:

A

Nafcillin or cephazolin (+/- gentamicin and rifampin if prosthetic valve)

If beta-lactam allergy: use vancomycin (+gentamicin and rifampin if prosthetic valve)

75
Q

IE treatment-
Organism: Staphylococcal (MRSA)
Preferred Abx regimen:

A

Vancomycin (+gentamicin and rifampin if prosthetic valve)

76
Q

IE treatment-
Organism: Enterococci
Preferred Abx regimen:

A

Penicillin or ampicillin + gentamicin (for both native and prosthetic valve IE)

If beta-lactam allergy, use vancomycin + gentamicin

If VRE, use daptomycin or linezolid

77
Q

Patients at high risk for IE during dental work + select cardiac conditions including:

A

Artificial (prosthetic) heart valve or heart valve repaired with artificial material

History of endocarditis

Heart transplant with abnormal heart valve function

Certain congenital heart defects including heart/heart valve disease

78
Q

Patients at high risk for IE during dental work + select cardiac conditions, adult PO prophylaxis regimen:

A

amoxicillin 2g 30-60min before dental procedure

79
Q

Patients at high risk for IE during dental work + select cardiac conditions, adult prophylaxis regimen, unable to take PO meds:

A

Ampicillin 2g IM/IV or

Cefazolin 1g IM/IV

80
Q

Patients at high risk for IE during dental work + select cardiac conditions, adult prophylaxis regimen, unable to take PO meds with cilin allergy:

A

Cephalexin or cefadroxil 2g or

Clindamycin 600mg or

Azithromycin or clarithromycin 500mg

81
Q

This is an infection of the peritoneal space that often occurs in patients with liver disease

A

Primary peritonitis, referred to as spontaneous bacterial peritonitis (SBP)

82
Q

The most likely pathogens of SBP are

A

Streptococci, enteric gram-negative organisms (Proteus, E. coli, Klebsiella/PEK) and, rarely, anaerobes

83
Q

Drug of choice for SBP

A

Ceftriaxone x5-7 days

Alt: ampicillin, gentamicin, or quinolone

84
Q

Primary or secondary prophylaxis of SBP

A

Bactrim, ofloxacin, and/or ciprofloxacin

85
Q

Secondary peritonitis is caused by a traumatic event (ulceration, ischemia, obstruction, surgery). Abscesses are common and should be drained.

The most likely pathogens are:

A

streptococci, enteric gram-negatives and anaerobes (B. Fragilis).

In more severe cases, coverage of pseudomonas and CAPES organisms may be necessary

86
Q

An acute inflammation of the gallbladder due to an obstructive stone:

An infection of the common bile duct:

A

Cholecystitis

Cholangitis

87
Q

Duration of intra-abdominal treatment (mild, severe, abscess)

A

4-7 days, mild
7-14 days, severe
>14 days, intra-abdominal abscess

88
Q

Management of secondary peritonitis and cholangitis - mild to moderate infections

Want to cover:

A

PEK, anaerobes, streptococci, +/- Enterococci

89
Q

Management of secondary peritonitis and cholangitis - mild to moderate infections

Therapy:

A

Possible regimens:
Cefoxitin
Ertapenem
Moxifloxacin
(Cefazolin, cefuroxime, or ceftriaxone) + metronidazole
(Ciprofloxacin or levofloxacin) + metronidazole

90
Q

Management of secondary peritonitis and cholangitis - high severity/ICU patients

Want to cover:

A

PEK, CAPES, pseudomonas, anaerobes, Streptococci +/- Enterococci

91
Q

Management of secondary peritonitis and cholangitis - high severity/ICU patients

Therapy:

A

Possible regimens:
Carbapenem (not erta)
Pip/tazo
(Cefepime or ceftazidime) + metronidazole
(Cipro or levo) + metronidazole
Cefazolin + (Aztreonam or AG) + metronidazole

92
Q

SSTI Classifications:
Mild -
Moderate -
Severe-

A

SSTI Classifications:
Mild - no systemic signs
Moderate - systemic signs (temp >100.4, HR>90, WBC>12k or <4k cells/mm)
Severe- failed PO abx+ incision and drainage if purulent, systemic signs, signs of deeper infection, immunocompromised

93
Q

Impetigo treatment for minimal lesions & numerous lesions:

A

Bacteriums: strep, s. aureus (MSSA)

Minimal lesions: topical mupirocin (Bactroban)

Numerous: Cephalexin (Keflex) 250mg PO QID

94
Q

Follicultis/furuncles/carbuncles treatment

A

If systemic signs, use abx that cover MSSA:
cephalexin (Keflex) 500mg PO QID

If non-responsive to initial tx, change to a drug with CA-MRSA coverage:

Bactrim DS 1-2 tabs BID
Doxycycline 100mg PO BID

95
Q

Cellulitis (non-purulent) treatment:

A

PO Abx must be active against streptococci (+/- MSSA):

Cephalexin 500mg PO QID
Clindamycin 300mg PO QID (if BL allergy
others: penicillin VK, docloxacillin)
x5 days

96
Q

Abscess (purulent) treatment:

A

If systemic signs or multiple sites: I&D, culture fluid, use PO Abx that cover CA-MRSA:

Bactrim DS 1-2 tabs BID
Doxycycline 100mg PO BID
Minocycline
Clindamycin

If MSSA –> Keflex

97
Q

Severe purulent SSTI treatment

A

duration x 7-14 days
Vancomycin
Daptomycin
Linezolid

Animal bite = amp/sulbactam, amox/clav

98
Q

Necrotizing Fasciitis treatment

A

Empiric therapy:

Vanc+beta-lactam (pip/tazo, imipenem/cilastatin, or meropenem)

99
Q

Treatment of moderate-severe diabetic foot infections/no MRSA coverage needed:

A
Ampicillin/sulbactam,
pip/tazo,
a carbapenem (imi/cilastatin, mero, erta)
moxifloxacin
x7-14 days
100
Q

Treatment of moderate-severe diabetic foot infections/ MRSA coverage needed:

A

Vancomycin plus one of the following:

ceftazidime, cefepime, pip/tazo, Aztreonam*, carbapenem (not erta)

Consider adding metronidazole on all the starred

101
Q
UTI sx:
-urgency and frequency
- painful urination
subrapybic heaviness
-blood in urine
A

Cystitis (lower UTI)

102
Q

UTI sx:

  • flank pain
  • fever, malaise
  • n/v, abdominal pain
A

Pyelonephritis (upper UTI)

103
Q

Acute uncomplicated cystitis treatment

A
Nitrofurantoin (Macrobid) 100mg PO BID with food x 5 days 
or
Bactrim DS 1 tab PO BID x 3 days 
or
Fosfomycin 3 g x 1 dose
104
Q

Acute uncomplicated cystitis treatment in pregnancy

A

Cephalexin, or amoxicillin

treat asx pregnant women x 3-7 days

105
Q

Acute uncomplicated cystitis treatment; can add this drug to relieve dysuria

A

phenazopyridine (pyridium) 200mg PO TID x 2 days MAX

106
Q

Acute uncomplicated pyelonephritis, moderately ill outpatient PO

A

if local resistant quinolone resistance <10%:

  • cipro 500mg PO BID (or cipro ER 1,000mg daily) x 7 days
  • levofloxacin 750mg PO daily x 5 dats

If local resistant quinolone resistance >10%

  • Ceftriaxone 1g IV/IM x1 or AG extended interval dose IV/IM x1, then continue with a quinolone as above x 5-7 days
  • Bactrim x 10-14 days
107
Q

Acute uncomplicated pyelonephritis, Beverly ill hospitalized patient (IV):

A

Initial: cipro or levo; gentamicin (+/- ampicillin, ceftriaxone, or pap/tazo); a carbapenem

Step down to PO tx options based on culture & sus

x14 days total (IV + PO)

108
Q

Complicated UTI Treatment

A

if local resistant quinolone resistance <10%:

  • cipro 500mg PO BID (or cipro ER 1,000mg daily) x 7 days
  • levofloxacin 750mg PO daily x 5 days

If local resistant quinolone resistance >10%

  • Ceftriaxone 1g IV/IM x1 or AG extended interval dose IV/IM x1, then continue with a quinolone as above x 5-7 days
  • Bactrim

Use a carbapenem if ESBL-producing present

x7 days if prompt sx relief
x10-14 days if delayed response

109
Q

Bacteriuria and Pregnancy treatment

A

Amoxicillin +/- clavulanate or an oral cephalosporin

Fosfomycin

While avoided in 1st trimester, Macrobid and Bactrim can be used in BL allergy

110
Q

Traveler’s diarrhea: treatment if dysentery is present

A

Azithromycin 1000mg PO x1 or 500mg PO dailyx1-3 days

111
Q

Traveler’s diarrhea: treatment if dysentery is not present

A

Quinolones (1-3 days) or rifaximin (3 days); loperamide to provide sx relief

Cipro 750mg PO x 1 or 500mg PO BID x 3 days
Levo 500mg PO x 1 or daily x 1-3 days
Olfloxacin 400mg PO x 1 or BID x 3 days
Rifaximin 200mg PO TID x 3 days

112
Q

C. Dif first episode non severe or severe treatment

A

vancomycin 125mg PO QID x 10 days, or

Fidaxomicin (Dificid) 200mg PO BID x 10 days

If above tx is not available and episode is non-severe: can use metronidazole 500mg PO TID x 10 days

113
Q

C. Dif second episode/first recurrence

A

If metronidazole was used for initial episode: vancomycin 125mg PO QID x 10 days

If Vanc was used for initial episode: fidaxomicin 200mg PO BID x 10 dats

If Vanc or Fidax used first, use tapered and pulse regimen

114
Q

DOC syphillis

A

Penicillin G berzathine (Bencillin L-A) 2.4 million units IM x 1

Alt: Doxycycline

115
Q

DOC Neurosyphilis and congenital syphilis

A

Pen G aqueous crystalline

Alt: Pen G procaine

116
Q

DOC gonorrhea

A

Ceftriaxone 250mg IM + azithromycin 1g PO x1 (or doxycycline)

MONOTHERAPY NOT RECOMMENDED

117
Q

DOC Chlamydia

A

Azithromycin 1g PO x1

118
Q

DOC Bacterial vaginosis

A

Metronidazole 500mg PO BID x 7 days

or Metronidazole 0.75% gel

or clindamycin 2% gel

119
Q

DOC trichomoniasis

A

Metronidazole 2g POx1; (ok in all trimesters)

or

Tinidazole 2g POx1

120
Q

DOC Genital warts (HPV)

A

Imiquimod cream (Aldara, Zyclara); tx not required if asx

Gardasil vaccine

121
Q

Gonorrhea & chlamydia often go together… treatment

A

(gonorrhea) Ceftriaxone 250mg IM + (chlamydia) azithromycin 1g or doxycycline 100mg BID x7 days

122
Q

Rickettsia Rickettsii causes Rocky Mountain spotted fever… treatment:

A

doxycycline 100mg PO/IV BID x 5-7 days (DOC in peds)

123
Q

Rickettsia typhi causes Typhus… treatment:

A

Doxy 100mg PO/IV BID x 7 days

124
Q

Borrelia burgdorferi, borrelia mayonii causes Lyme disease… treatment:

A

Doxycycline 100mg PO BID x 10-21 days, or

amoxicillin 500mg PO TID x14-21 days, or

Cefuroxime 500mg PO BID x 14-21 days

125
Q

Ehrlichia chaffeensis causes ehrlichiosis…treatment:

A

doxycycline 100mg PO/IV BID x ist 7-14 days

126
Q

Francisella tularensis causes Tularemia… treatment:

A

Gentamicin or tobramycin 5mg/kg/day IV divided Q8H x7-14 days

127
Q

Tinea corporis treatment

A

clotrimazole or another topical fungal