Allergic Rhinitis, Cough & Cold Flashcards

1
Q

What is hay fever?

A

Allergic rhinitis, or simply “allergies”

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2
Q

While colds are caused by a virus, allergic rhinitis is caused by?

A

an allergen (pollen dust, pet dander)

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3
Q

Non-drug treatment for allergic rhinitis?

A

Avoiding exposure to known or suspected allergens

an IgE-mediated skin prick test or blood test can determine patient-specific allergens

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4
Q

Common allergens (4)

A

Pollens

Molds

Dust mites

Animal dander

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5
Q

What is the name of the index that rates the local air as good to hazardous?

A

AQI - air quality index

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6
Q

Nasal irrigation uses what types of saline solution?

A

isotonic and hypertonic (2-3.5%)

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7
Q

What is first line for chronic, mod-severe symptoms of allergic rhinitis?

A

intranasal steroids

especially effective in reducing the nasal symptoms of allergic rhinitis, congestion

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8
Q

What is first line for milder, intermittent symptoms?

A

oral antihistamines

little effect on nasal congestion

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9
Q

Brand: Rhinocort Allergy

A

Generic: budesonide

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10
Q

Brand: Flonase Allergy Relief, Flonase Sensimist, Children’s Flonase

A

Generic: fluticasone

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11
Q

Brand: Nasacort Allergy 24H & in children’s

A

Generic: triamsinolone

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12
Q

What is a common side effect from intranasal steroids?

A

epistaxis (nose bleeds)

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13
Q

How long can it take for nasal steroids to work?

A

1 week

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14
Q

What are the preferred nasal steroids in pregnancy?

A

budesonide and beclomethasone (Beconase AQ)

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15
Q

Antihistamines work by blocking histamine at the ___ receptor site

A

H1

first gen- more sedative

second gen- less

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16
Q

diphenhydramine
chlorpheniramine
doxylamine
clemastine

drug class?

A

First gen oral antihistamines

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17
Q

Brand: Aller-Chlor, Chlor-trimeton

A

Generic: Chlorpheniramine

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18
Q

Benadryl dose for adults

A

25-50mg PO Q4-6h (max 300mg/day)

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19
Q

Benadyl <6 y dose

A

do not use OTC, unless directed by PCP

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20
Q

Which drug class?

avoid in elderly
prostate enlargement
glaucoma
somnolence, cognitive impairment

A

first-get antihistamines

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21
Q

cetirizine
levocetrizine
fexofenadine
loratadine

drug class?

A

second gen antihistamines

22
Q

Brand: Zyrtec

A

Generic: cetirizine

23
Q

Brand: Xyzal Allergy

A

Generic: levocetirizine

24
Q

Brand: Allegra Allergy

A

Generic: fexofenadine

*don’t take with juice

25
Brand: Claritin
Generic: loratadine
26
What second gen drugs are preferred in preg?
loratadine, cetirizine
27
Cetirizine and levocetirizine more or less sedating?
MORE less= fexofenadine, loratadine
28
Can intranasal antihistamines be combined with intranasal steroids?
yes dymista, patanase
29
alpha-adrenergic agonists that cause vasoconstriction which decreases sinus vessel engorgement and mucosal edema
decongestants
30
Oral decongestants include
phenylephrine | pseudoephedrine
31
Which drug class? C/IL within 14 days of MAO inhibitors avoid in children <2 (FDA) caution with CVD, BPH, urinary retention inc HP, BP
Oral decongestants
32
oxymetazoline (afrin) is a ..
intranasal/topical decongestant
33
An OTC mast cell stabilizer used for treatment and prophylaxis of allergic rhinitis
Intranasal cromolyn (NasalCrom) used regularly, not PRN to be effective; safe in kids and preg
34
the only leukotriene modifying agent indicated for the treatment of both allergic rhinitis and asthma
montelukast (Singulair) FDA- BW for neuropsychiatric effects
35
contains 5 different grass pollen extracts
Oralair
36
contains Timothy grass pollen extract
Grastek
37
contains ragweed pollen extract
Ragwitek
38
Contains house dust mite allergen extract
Odactra
39
Natural products used for colds?
Zinc Vitamin C Echinacea Airborne/Emergen-C
40
acts as a serotonin reuptake inhibitor, at high doses it acts as an NMDA-receptor blocker leading to euphoria and hallucinations similar to PCP
dextromethorphan "DM" many states ban the sale to minors
41
Codeine listed as a CII used for:
pain
42
Codeine listed as a C-V used for:
cough and cold
43
BW: respiratory depression and death have occurred in children who have received this drug following tonsillectomy and or adenoidectomy and have evidence of being ultra-rapid metabolizers due to a 2D6 polymorphism
Codeine do not use in children <12 or <18 for said surgeries
44
The FDA recommends to avoid codeine-containing cough and cold products for patients
<18
45
Brand: Tessalon Perles
benzonatate
46
Brand: Bromfed DM
Generic: Brompheniramine/psueoephedrine/dextromethoprphan
47
AC means what is inside?
codeine
48
Brand: TussiCapsm
Generic: Chlorpheniramine/hydrocodone | C-II
49
Promethazine/codeine control?
C-V
50
guafenensin/codeine control?
C-V
51
Guafenesin/codeine/pseudoephdrine control?
C-V
52
What products need to be avoided in children <2?
OTC cough and cold products promethazine topical menthol and camphor (Vicks)