Incorrect MCQ - Cross Species Flashcards
Ergot intoxication is primarily associated with which clinical signs?
Necrosis of extremities and gangrene.
May also see CNS signs.
Ergot intoxication is caused by the ingestion of ?
Alkaloids in the parasitic fungus Claviceps purpurea. This fungus infects grains such as rye and wheat. bromes, bluegrass, and ryegrass.
Give an example of a Phosphodiesterase inhibitor.
Pimobendan
What is the MOA of Phosphodiesterase inhibitors?
Phoshodiesterase inhibitors are positive ionotropes so they increase the strength of cardiac contractility by making more Ca2+ available.
An increase in what immunoglobulin would make you suspicious for current toxoplasmosis infection in a pregnant human patient?
IgM
IgG positive = previous infection
Toxoplasmosis will only cause birth defects in a fetus if the mother is infected for the FIRST time.
Abnormalities in the frontal cerebral cortex, also known as the ___________, would result in what clinical signs?
Cerebrum
Blind with normal PLR
Seizures
Compulsive pacing
Dementia
Lack of owner recognition
What is the difference between elastic vs inelastic demand?
Inelastic demand = the % difference in # of procedures performed is lower than the % difference in the price increase.
- Hospital makes MORE MONEY by raising the price.
Elastic demand = the % difference in # of procedures performed is greater than the % difference in the price decrease.
- Hospital makes more money by LOWERING the price.
From the choices listed below, which affect the healthiest, fastest-growing animals in a group?
Clostridium perfringens type C and shiga-toxin producing E-coli
Edema disease primarily affects what species and within what age range?
Primarily affects nursery age piglets.
- Usually occurs 1-2 weeks after weaning and always affects the HEALTHIEST animals in the group.
What are the major clinical signs of Edema disease?
Facial/periocular edema, CNS signs such as ataxia, paralysis.
- in some cases may see NO clinical signs.
How do you treat edema disease?
Treatment is often ineffective, but antimicrobials in the water may help prevent clinical disease in unaffected pigs.
There are several vaccines now available.
Clostridium Perfringens Type C is seen in what species and of what age range?
Healthy, fast growing calves
(also affects lambs)
What are the major clinical signs associated with Clostridium Perfringens Type C?
In calves - acute diarrhea, dysentery, abdominal pain, seizures, opsithotonos, and death.
What test is used to confirm protein-losing enteropathy in small animals?
Fecale A-1 proteinase inhibitor
Same size as albumin so it is lost via the GIT HOWEVER fecal a-1 proteinase inhibitor is resistant to digestion so that is why it can be measured.
How do you treat Clostridium Perfringens Type C?
Treatment often ineffective
What is the MOA of Pralidoxime Chloride (2-PAM) in the tx of OP toxicosis?
2-PAM blocks binding of toxin to acetylcholinesterase.
Why is this important? Toxins bind to acetylcholinesterase –> build up of Ach at muscarinic receptor –> seizures, convulsions, etc.
What is an example of a Type I immune reaction?
Anaphylaxis
What is an example of a Type II immune reaction?
Ag + Ab complex formation –> lysis
Example = IMHA
What is an example of a Type III immune reaction?
Ag + Ab complex formation –> deposited on endothelium
Example = Glomerulonephritis, SLE, purpura hemorrhagica, anterior uveitis, vasculitis
What is an example of a Type IV immune reaction?
Delayed hypersensitivity reaction
- are cell mediated
How can you tell, when looking at an ECG, if a patient is experiencing premature ventricular contractions?
There will be QRS waves going off without a P wave b/c depolarization is occurring in the ventricles and completely bypassing the atria.
When looking at an ECG, how can you tell a patient is experiencing a bundle branch block?
The QRS complexes are oddly shaped!
This is because the conduction pathway is normal up until it reaches a point in the heart where a bundle is blocked.
Cochliomyia is a genus of _________.
Is this disease still found in North America?
Screwworm
It has been eliminated in North America but is still found in South America and Caribbean countries.
What is healing by second intention?
Healing by second intention is when a wound is not only dirty but you also fear that suturing it closed would fail so you debride as much as possible and let it granulate, epithelialize, and contract to closure.
Holstein cattle are genetically predisposed to developing what disease?
Cystic ovarian disease due to insufficient release of GnRH –> persistent follicles b/c no LH surge to prompt ovulation.
Mild loss of skin turgor is associated with what % of dehydration? Severe loss of skin turgor?
6-7%
8-10%
In a case of Nutritional Secondary Hyperparathyroidism in a horse, what would you expect to see on BW?
Increased parathyroid hormone
Increased phosphorous
Normal to low calcium
Always think High P, Low Ca for this disease
When you see dead calves and peri-renal edema, think oak poisoning. In the spring, oak acorns contain high levels of nephrotoxic tannins
Define hygroma.
Hyogromas are nonpainful fluctuant swelling of soft tissue that has suffered repeated trauma.
Often see in the tarsus of cattle and the elbow or carpus of horses.
When can you reliably feel the following in a pregnant cow:
- Chorionic membrane slip
- Placentomes
- Fremitus
- Chorionic membrane slip: 30-35 days
- Placentomes: 70-75 days
- Fremiturs: 120-150 days
What is the most common nasal tumor in cats? Tx of choice?
Lymphoma; radiation therapy
List the species that are induced ovulators:
Llamas, ferrets, cats, rabbits, south american camelids
List the species that are spontaneous ovulators:
Dogs, guinea pigs, sheep, rodents
Distemper
What are the most common clinical signs seen in birds infected with polyomavirus?
Acute onset of lethargy, crop stasis, death within 24-48 hrs. Subcutaneous hemorrhage is also often reported.
Epiglottic entrapment for fucks sake
Diagnose what is in the image
Dorsal displacement of soft palate
T/F: Vesicular stomatitis commonly causes clinical disease in small ruminants.
FALSE
It rarely causes clinical disease in small ruminants
What does Erysipelothrix rhusiopathiae cause in small ruminants?
Nonsuppurative polyarthritis
You are presented with a flock of sheep with the following C/S:
- Edema and hyperemic skin lesions on the udders and coronary bands
- Ulcerations of the oral mucous membranes
What is your most likely differential?
Bluetongue
Imidocarb diproprionate is the most effective therapeutic agent against what orgnaism?
Babesia canis
DON aka vomitoxin (real name: Deoxynivalinol) is commonly found in corn and other grains harvested during times of HIGH MOISTURE. Imparts an aversive taste and animals will rarely eat feed.
Tx: Replace feed or blend contaminated feed with uncontaminated feed to decrease toxin concentration OR scrub grains to remove fungus.
If you see two week old rats in a colony with dry skin and annular constrictions of their tails, what should you do?
Increase humidity and decrease room temperature - this is ringtail!
Humidity should be maintained around 40-70%, room temp around 70-74F
When is the best time to reduce twins found in a pregnant mare?
14-16 days b/c day 16 is the day of implantation and after this point the embryo is too large to be easily seen on US.
If you miss this window, you can also reduce at day 35-40 when the endometrial cups start to form.
Euthanizing one of the fetuses is recommended since twins are detrimental to health of mare.
What breathing pattern is this?
Cheyne-Stokes pattern
Occurs when there is direct or ischemic damage to the brain, cerebral edema and/or increased intracranial pressure is present.
Can also happen if too deep under anesthesia
What suture type (monofilament or multifilament) is better for skin wounds and why?
Monofilament because less likely to wick bacteria leading to wound infection. Also less tissue drag during suture procedure.
You are presented with a horse that displays exaggeration of upward flexion of one or both hindlimbs. What is your top differential? Etiology? Dx? Tx?
Stringhalt
Idiopathic or sporadic - both associated with a neuropathy. Sporadic associated with ingestion of dandelion (Hypochoeris radicata).
Tx: Remove inciting cause, Intraarticular steroids. If medical management does not work - Sx on lateral digital extensor tenectomy (results are inconsistent).
A seven-year-old male neutered Labrador retriever is presented with a five-month history of intermittent left pelvic limb lameness.
Radiographs of the left hock are shown below.
What is the primary lesion of concern?
There is a fracture in an oblique orientation of the proximal talus. This is best seen on the cranio-caudal projection.
Other radiographic findings: There is new bone proliferation on the medial and lateral aspects of the talus near the fracture margin. There is increased soft tissue opacity at the level of the tarsocrural joint indicating effusion.
Surgically reduce and stabilize tarsal fractures. In some cases, arthrodesis is the best choice.
Define paronychia.
Swelling around a single nail bed, caused by neoplasia, infection, or immune-mediated disease.
Define onychorhexis
Brittle nails that are split or easily broken.
Multiple in dachshunds are idiopathic.
Generalized infections - dermatophytosis or leishmaniasis.
Define onchymycosis
Fungal infection of nail bed
Define onychomadesis
Sloughing of the nail off the nail bed.
List the parameters for septic peritonitis in horses:
- serum-to-peritoneal glucose difference > 50 mg/dL
- peritoneal fluid pH < 7.2
- Cytology showing > 90% of cells are degenerate neutrophils with free and phagocytosed bacteria
- increased lactate > 2
- serum amyloid A > 10
What is a common cause of acute colitis and diarrhea in adult horses?
Salmonella
Commonly occurs due to AB treatment or admission to hospital for colic.
This is why macrolides, like erythromycin, should be used with caution in horses.
What is an important cause of sepsis in newborn foals?
E.coli
Normal!
What would you see in a case of cholecalciferol toxicity in a cat?
Severe hypercalcemia and acute renal failure secondary to renal calcification.
Philodendron plants contain?
Calcium oxalate so when ingested in excess you would see oxylate crystals causing renal failure + oral inflammation and swelling NOT HYPERCALCEMIA
What are the top differentials for a thin camelid?
GI parasites
poor dentition or nutrition
Johnne’s disease
Mycoplasma haemolamae
eosinophillic enteritis
BVDV
GI ulceration
neoplasia such as lymphosarcoma or SCC
Imidocarb dipropionate (Imizol®) and fluids (with quarantine) are the treatments of choice for equine babesiosis. Can also use diminazine diaceturate (Berenil®) but Tx is complicated and depends on if horse lives in endemic country, and has acute/chronic/subacute Dz.
Babesiosis (or piroplasmosis) is a tick-borne disease caused by the apicomplexan protozoan parasites, Babesia caballi and Theileria equi. It is of huge economic importance in endemic regions (not the U.S./Canada), and is rarely reported in the southern gulf-coast region of the U.S.
Which of the following statements about temperature control in aquatic systems is most accurate?
E
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Which one of the following methods is the best way to prevent infection with bovine viral diarrhea (BVD) in South American camelids?
Strict biosecurity
What are the two main causes of pregnancy toxemia in guinea pig sows?
Ketosis and hypertension
What is a common cause of urethral obstruction in male ferrets?
Enlarged prostate (prostatic hypertrophy) secondary to hyperadrenocorticism.
A three-year-old budgerigar (parakeet) with a two-week history of respiratory infection and clogged sinuses is presented. She has been on and off sick over the last two months, and does not appear to be responding to doxycycline mixed into her feed for the last month.
She presents with feathers puffed up, and white plaques around her mouth and eyes. Her eyes seem to be
“bugged out” (exophthalmia).
What condition is at the top of the differential diagnosis list?
Treat this enteric septicemia of channel catfish with antimicrobials based on culture results with an FDA-approved medicated feed. Caused by the gram-negative bacteria Edwardsiella ictaluri, it is the most important infectious disease of the catfish industry.
Death rates are worsened by stress and handling, poor water quality, and recent chemical treatment of the water. Most likely to occur in spring/fall when water temperatures stay between 71.6-82.4°F (22-28°C).
There are enteric and meningeal forms. Enteric causes hemorrhagic enteritis with punctate, red lesions along the body wall and petechial hemorrhages around the eyes and mouth. Meningeal causes “hole in the head” in fingerlings and disoriented/spinning behavior.
There are available vaccines for prevention.