General Info - Bovine Flashcards
Zearalenone is made by?
Fusarium spp. infecting grains and forage.
What are the clinical signs of Zearalenone?
Increased or inappropriate estrus behavior, prolonged estrus cycles, vulvovaginitis, hypertrophy of the clitoris.
What species are affected by Zearalenone toxicity?
Cattle, pigs, poultry most severely affected. Sheep are most resistant
Zearalenone toxicity
Trichothecenes is made by?
Fusarium spp. infecting cereral grains and inhibit protein synthesis by binding ribosomes.
What is the most common Trichothecenes?
DON
What are the clinical signs of Trichothecenes toxicity?
Most common C/S: feed refusal, poor growth rates, necrotic mucosal lesions in oral cavity/distal GI tract, hypersalivation, vomiting in monogastrics, immunosuppression
What are the C/S of Slaframine ingestion?
THINK: SLOBBER FACTORS
Hypersalivation within 24 hrs, anorexia, diarrhea, bloat, polyuria
Slaframine is produced by?
Slafractonia leguminicola infecting RED CLOVER.
What are the C/S of aflatoxin ingestion?
Inappetance, anorexia, vomiting, depressiong, hemorrhage, sudden death
What are the C/S of Fumonisin ingestion?
There are two clinical diseases:
- Equine leukoencephalomalacia: depression, sleepiness, circling, incoordination, pharyngeal paralysis and recumbency; nearly always fatal
- Porcine pulmonary edema: dypsnea, cyanosis, weakness, abortion, recumbency and death within 24 hrs
T/F: Adsorbents are FDA-approved in the US.
False - none of them are
What adsorbent is effective against aflatoxins?
Aluminosilicates
Aflatoxins are produced by?
Aspergillus spp.
Aflatoxins are?
Carcinogemic, mutagenic, teratogenic
Fumonisin is produced by?
Fusarium infecting corn
Gossypol toxicity results in?
GI: anorexia, colic, diarrhea
Cardiac: cardiac arrest in cases of acute exposure, CHF.
Other: violent thumping (dypsnea) in pigs
Post-mortem: streaked, pale myocardium, subcutaneous edema, straw-colored effusions
Describe gossypol pathogenesis:
Cattle are fed cottonseed meal/cottonseed containing gossypol toxic pigment over the course of several months –> binds to iron and inhibits absorption –> erythrocyte fragility, ETC inhibited, thyroid hormone production inhibited.
What is the difference between severity score 1,2, and 3 in regards to bovine mastitis?
1 = one udder quarter is affected
2 = entire udder is affected
3 = cow is sytemically ill
List the environmental causes of mastitis:
E.coli, Klebsiella, Streptococcus, Enterobacter, Proteus, Serratia, Coag (-) staph
List the contagious pathogens of mastitis:
Strep agalactiae, staph aureus, trueperella pyogenes, mycoplasma
Healthy cows have a somatic cell count of?
< 100,000
List the parameters for acceptable milk to be consumed by humans:
SCC
Coliforms
Bacteria
SCC < 750,000/,ml
Coliforms < 10/ml
Bacteria < 100,000/ml
How would you treat a mastitis severity score of 1 or 2 and + culture for gram + bacteria?
Intramammary AB
How would you treat a mastitis severity score of 1 or 2 and + culture for gram - bacteria?
No tx, immune system will clear pathogen
discard milk until it returns to normal
How would you treat a mastitis severity score of 3?
Systemic AB, fluids, electrolytes, flunixin meglumine, nutritional support, milk out affected quarters