General Info - Canine Flashcards
You recently diagnosed a canine patient with Hyperadrenocorticism. What would you expect to see on this patient’s bloodwork in order to have helped you reach this conclusion?
- Elevated ALP
- Hypercholesterolemia
- Hyposthenuria +/- proteinuria
- Stress leukogram = neutrophilia, eosinopenia, lymphopenia
What is the function of trilostane?
Inhibits cortisol producing enzyme
What is the function of Lysodren?
Kills cells in adrenals that makes cortisol
What is the difference between IVDD seen in chondrodystrophic breeds vs nonchondrodystrophic breeds?
Chondrodystrophic: Nucleus pulposus extrudes through the annulus fibrosus.
Nonchondrodystrophic: Hypertrophy/bulging of the annulus pulposus.
The heartworm snap test detects?
Adult female worms 5+ mo post infection
List the intermediate hosts of heartworm disease:
Aedes, Anopeles, Culex
Fipronil kills?
Adult fleas
Brands to think of: Frontline plus
Lufeneuron does?
Inhibits flea development
Brands to think of: Sentinel
List the radiographic changes/signs of canine hip dysplasia:
- Flattened femoral head
- Poor femoral head coverage
- Shallow acetabulum
- Femoral head/neck thickening
What % of the femoral head is covered by the acetabulum in canine hip dysplasia patients?
50%
When is PennHIP most accurate?
Early in life than OFA
Who are the poster children for panosteitis?
Vizlas
What is the difference, in terms of physical exam findings, between panosteitis, HOD, and OCD?
Panosteitis: pain on long bone (femur, humerus, radius, ulna, tibia) palpation.
HOD: pain when palpating near metaphysis
OCD: Joint effusion, decreased range of motion.
What is the difference, in terms of radiographic findings, between panosteitis, HOD, and OCD?
Panosteitis: increased medullary opacity, periosteal new bone.
HOD: “double physis”
OCD: flattening of femmoral head, joint mice, effusion
What clinical signs are seen with ethylene glycol toxicity @ 1-2 hrs & 24-72 hrs?
1-2 hrs = stuporous, disoriented, nauseous
24-72 = renal failure signs, vomiting, anorexic, PU/PD,
The Ethylene glycol test is only good for what amt of time post ingestion?
30 min - 12 hrs
How long does it take for calcium oxalate crystals to form in EG patients urine?
3-18 hrs
An osmole gap of = is suggestive of EG toxicity?
osmole gap > 20
What is the MOA of Fomepizole in treating EG toxicity?
Prevents conversion of EG to toxic metabolites.
Parvovirus is what type of virus?
Nonenveloped single stranded DNA virus
Parvovirus attacks?
Bone marrow, lymphopoietic tissue, and small intestinal crypts –> villous blunting
You are presented with a 5 yr old lab that is experiencing weight gain, lethargy, exercise intolerance, bilateral nonpruritic alopecia with a rat tail, and dry coat.
You suspect your patient has Hypothyroidism and want to run some tests to confirm your suspicions. What would you expect for the following values:
Total T4
Free T4
TSH
Explain your thought process
In patients with hypothyroidism, you would typically see a low T4 (but this is not confirmatory of true hypothyroidism, so need to check Free T4 and TSH. If free T4 is low = true hypothyroidism, if normal = sick euthyroid syndrome. Lastly, if TSH is high = true hypothyroidism, if normal or low = most likely sick euthyroid syndrome.
Pre-renal vs renal vs post renal azotemia
List the etiologies of kennel cough
Bordatella bronchiseptica, canine adenovirus 2, canine influenza virus H3N8 & H3N2, Mycoplasma, canine parainfluenza, +/- distemper virus
What two drugs can cause temporary megaesophagus?
Ketamine, xylazine
Which cystic calculi are radioopaque?
Struvite, calcium oxalate, calcium phosphate, silica, +/- cystine
How would you treat a case of cystitis or struvite crystals?
AB or sx or medial dissolution with diet.
How would you treat a case of calcium oxalate or phosphate crystals?
Sx and low protein alkaline promoting urine diet
How would you treat a case of cystine crystals?
Low protein and low methionine for 1 mo past dissolution then low protein renal diet
List the etiologies for fleas in canids and felids:
Felids: C. felis
Canids: C. canis
List the etiologies for mites in canids and felids:
Sarcoptes scabei, Cheyletiellosis
T/F: Dogs are usually infected with cat fleas
True
How do you treat flea infestation in dogs?
Fipronil in puppies > 8 weeks of age
Lufenuron or Selamectin in puppies > 6 weeks of age