Immunology Flashcards

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1
Q

major histocompatibility complex

A

consists of a linked set of genetic loci encoding many of the proteins involved in antigen presentation to T cells

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2
Q

NK cells (Natural Killer Cells)

A

effector lymphocytes of the innate immune system that control several types of tumors and microbial infections by limiting their spread and subsequent tissue damage.

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3
Q

Innate Immunity

A

present before any exposure to pathogens and is effective from the time of birth.

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4
Q

Innate immunity consists what?

A

external barriers, cellular, and chemical defenses

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5
Q

What type of responses does innate immunity have?

A

non specific

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6
Q

Acquired Immunity

A

develops after exposure to agents such as microbes, toxins, or other foreign substances

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7
Q

What type of response does acquired immunity give?

A

specific

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8
Q

What helps with acquired immunity

A

lymphocytes

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9
Q

B cells

A

produce antibodies

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10
Q

T cells

A

activate other cells

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11
Q

What speed do each of the responses have?

A
  • Innate immunity - rapid response
  • Acquired Immunity - slower response
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12
Q

How does a microbe get destroyed?

A

A white blood cell engulfs a microbe, then fuses with a lysosome to destroy the microbe.

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13
Q

What are the different types of phagocytic cells?

A
  • Neutrophils
  • Macrophages
  • Eosinophils
  • Dendritic Cells
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14
Q

Neutrophils

A

engulf and destroy microbes

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15
Q

Macrophages

A

part of the lymphatic system and are found throughout the body.

-Main phagocytes (aka. monocytes)

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16
Q

Eosinophils

A

discharge destructive enzymes.

17
Q

Dendritic Cells

A

stimulate development of acquired immunity.

18
Q

Where is MHC2 protein molecules?

A

They are found on antigen presenting molecules

19
Q

What can be a reason for a cell no longer expressing MHC protein?

A

cancerous or infected

20
Q

Mast Cells

A

release histamine

21
Q

Histamine

A

increase local blood supply and allow more phagocytes and antimicrobial proteins to enter tissues.

22
Q

Fever?

A

systemic inflammatory response triggered by pyrogens released by macrophages, and toxins from pathogens.

23
Q

Septic Shock

A

a life-threatening condition caused by an overwhelming inflammatory response.

24
Q

What type of proteins does are on B cells and T cells

A

receptor proteins

25
Q
A