Immunity Flashcards
Two properties distinguish between adaptive immunity and
innate immunity:
Specificity and memory
for foreign molecules which act as Ag
● this involves distinguishing self-molecules (normal, not antigenic) from
nonself molecules
Specificity
For previously encountered Ag
Memory
Not all foreign substances are antigenic:
● Molecules, or parts of molecules tend to be antigenic if theyare:
Organic
Structurally complex
Large
Lymphocytes (B and T cells) recognize antigens (Ag).
● During development, Each lymphocyte
___ selects
_____antigen to attack
Randomly. One Specific
That the immune system derives from the body it is protecting 
Self antigen
B cells mature in
Bone marrie
T cells mature in
Thymus
lymphocyte will rapidly reproduce and differentiates when activated by its specific antigen.
Clonal Selection
population of identical cells, all recognizing the same antigen as the original cell.
Clone
Lymphocytes undergo clonal selection to produce:
Effector and memory cells
produce the immune response and die after the immune response. (once the antigen is removed)
Effector
do not participate in the initial immune response but are able to rapidly respond to a subsequent exposure - proliferating and differentiating into more effector and memory cells.
Memory
dendritic cells and
macrophages
● Link innate and adaptive
immune systems.
Dendritic cells: usually found in tissues in contact with the external environment
The most potent of the antigen-presenting cell types.
Antigen-presenting cells (APCs):
engulfs and destroys a foreign invader
● Then isolates the antigens on the invader
● The___ then presents the foreign Ag to a specific T lymphocyte called a helper T cell Processed Ag (also known as a CD4 cell) .
is presented
APC
