Hypothalamus and Limbic System Flashcards
What is the primary role of the hypothalamus?
Homeostasis
What is the rostral/anterior boundary of the hypothalamus?
Optic chaism
What is the caudal/posterior boundary of the hypothalamus?
Tegmentum and PAG
The hypothalamus forms the floor and ventral walls of?
3rd ventricle
The hypothalamus continues inferiorly through?
Infundibular stalk with posterior pituitary
What forms the posterior part of the hypothalamus and are adjacent to the cerebral peduncles?
Mammillary bodies
What is the floor of the hypothalamus and are small swellings between the mammillary bodies and the optic chiasm and tract?
Tuber cinereum
What arises from the tuber cinereum and narrows into the infundibulum and attaches to pituitary gland?
Median eminence
What is the area immediately adjacent to the 3rd ventricle and blends with PAG?
Periventricular zone
What divides the remainder of hypothalamus into medial and lateral zones?
Fornix
What is the characteristic of neurons within the lateral zone?
They are diffusely arranged and do not have solid boundaries
If you lesion the lateral zone what occurs?
Decrease in feeding behavior resulting in weight loss
Where is the median forebrain bundle located?
Lateral zone
What nuclei release oxytocin?
ADH?
1) Paraventricular nucleus
2) Supraoptic
What nuclei are critical for posterior pituitary regulatory function?
Supraoptic and paraventricular nucleus
What happens if you lesion the supraoptic and paraventricular nucleus?
1) Diabetes insipidus
2) Increase in H2O intake
3) Increase urination
What nucleus is in the supraoptic region and receives retinal input and is involved in circadian rhythms?
Suprachiasmatic nucleus
What happens if you lesion the Suprachiasmatic nucleus?
May modify or abolish circadian rhythms
What nucleus is in the supraoptic region and does a range of visceral/somatic functions such as temperature regulation?
Anterior nucleus
What nucleus is in the posterior region and receives afferents from the hippocampus via the fornix and sends efferents to the thalamus and brainstem?
Medial mammillary nucleus
Lesion to the medial mammillary nucleus results in what?
Inability to process short term events into long term memory
What nucleus is in the tuberal region and is considered to be a satiety center?
Ventromedial nucleus
What happens if you lesion the ventromedial nucleus?
Excessive eating and abnormal weight gain
What nucleus is in the tuberal region and subserves functions of emotional behavior?
Dorsomedial nucleus
Stimulation of the dorsomedial nucleus in animal models can cause?
Sham rage
What happens if you lesion the dorsomedial nucleus?
Decrease in aggression and feeding
What arteries serve the preoptic area and supraoptic region, septal nuclei, and rostral portion of lateral hypothalamic area?
Branches from anterior communication and A1 of ACA
What artery serves the tuberal region?
Rostral portion of posterior communicating artery
What artery serves the mammillary region?
Caudal parts of posterior communicating artery
What afferent arises from the subiculum and hippocampus and is the largest single input to the hypothalamus?
Fornix
What afferent interconnects septal nuclei, hypothalamus, and midbrain tegmentum while also coursing through lateral hypothalamic zone?
Medial forebrain bundle