Human disease L24: Renal disease Flashcards

1
Q

does the ureter come before or after the bladder

A

before

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2
Q

if the kidney was disected, you could see the distinction between the inner and outer part of the kidneys.

what is the name of these anatomical features

A

cortex = outer part of kidney

medulla = inner part of kidney

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3
Q

where do all the collecting ducts feed in to in the kidney

A

renal pelvis

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4
Q

the formation of a “ball” of arterioles in the kidney is known as a what

A

glomerulus

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5
Q

what is the function of the bowmans capsule

A

Bowman’s capsule surrounds the glomerular capillary loops and participates in the filtration of blood from the glomerular capillaries.

Bowman’s capsule also has a structural function and creates a urinary space through which filtrate can enter the nephron and pass to the proximal convoluted tubule

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6
Q

the arterioles that come in to the glomerular capsule / bowmans capsule are called what

A

afferrent arterioles

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7
Q

what occurs at point a

A

water and solutes smaller than proteins are forced throughthe capillary walls and pores of the glomerular capsule into the renal tubule

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8
Q

what occurs at point b

A

tubular reabsorption

water, glucose, amino acids, and needed ions are transported out of the filtrate into the tubule cells and then enter the capillary blood

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9
Q

what occurs at point c

A

tubular secretion

H+, K+, creatine and drugs are removed from the peritubular blood and secreted by the tubule cells into the filtrate

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10
Q

which hormone maintains equilibrium between NaCl and H2O

A

Anti diuretic hormone

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11
Q

acid base balance is regulated by the kidneys in conjunction with the lungs.

which acid and base is excreeted

A

H+ = acid

HCO3 = base

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12
Q

is CO2 acidic or alkali in solution?

A

acidic

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13
Q

is a condition in which there is too much acid in the body fluids.

A

acidosis

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14
Q

is a condition in which there is too much base in the body fluids.

A

alkalosis

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15
Q

if we have a state of acidosis in our body what would the body do rid of the excess acid

A

breathe more quickly to breathe off more CO2

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16
Q

what triggers diabetic ketoacidosis

A

Diabetic ketoacidosis (DKA) is a serious condition that can lead to diabetic coma (passing out for a long time) or even death.

When your cells don’t get the glucose they need for energy, your body begins to burn fat for energy, which produces ketones.

ketones are acids.

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17
Q

what are ketones

A

Ketones are a type of chemical that your liver produces when it breaks down fats. Your body uses ketones for energy typically during fasting, long periods of exercise, or when you don’t have as many carbohydrates. You can have low levels of ketones in your blood without it being a problem.

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18
Q

what would the respiratory rate be for someone suffering from diabetic ketoacidosis

A

high respiratory rate

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19
Q

the kidney is responsible for producing hormones, what is the name of the hormone that produces red blood cells

A

erythropoietin

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20
Q

where is renin produced and what does it do?

A

renin is produced in the kidneys and responsible for the conversion of angiotensin to angiotensin 1.

part of the renin angiotensin aldosterone system of blood pressure control.

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21
Q

what is the name for this HCO3-

A

Bicarbonate

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22
Q

if you have high potassium levels due to renal failure, what can that lead to. what is the name given for having high potassium levels

A

high potassium levels is known as hyperkalaemia and can lead to cardiac arrest

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23
Q

according to mayo clinic, what is the normal range of potassium in blood

A

3.6 to 5.2 millimoles per liter (mmol/L) of blood

A potassium level higher than 5.5 mmol/L is critically high, and a potassium level over 6 mmol/L can be life-threatening.

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24
Q

is a disorder of kidney function that occurs when the kidneys cannot properly remove urea from the body, so waste from urine accumulates in the blood and another series of diseases can occur.

name the disorder

A

uraemia

25
Q

what is a nephrologist

A

A nephrologist is a type of doctor that specializes in treating diseases of the kidney

26
Q

the accumulation of waste products in your system, as a result of renal failure is known as what

A

uraemia

27
Q

refers to an overall feeling of discomfort and lack of well-being. Fatigue is extreme tiredness and lack of energy or motivation for everyday activities.

what is being referred

A

malaise

28
Q

what is the term used when you produce allot of urine

A

polyuria

29
Q

what is the term given when producing little amount of urine

A

oliguria

30
Q

what term is given when you produce no urine

A

anuria

31
Q

what is present in your urine if you have haematuria

A

blood

32
Q

what is present in your urine if you have proteinuria

A

protein

33
Q

what is present in your urine if you have glycosuria

A

glucose

34
Q

what is the term given if you experience pain whilst passing urine

A

dysuria

35
Q

wat is the term given if you frequently pass urine in the night

A

nocturia

36
Q

a normal eGFR would show a meaasurement of what

A

>60mls/min

37
Q

if you have stage 5 kidney disease (the last stage) what percentage of your kidney is functioning

A

less than 15%

38
Q

renail failure - acute or chronic

rapid onset

A

acute renal failure

39
Q

renail failure - acute or chronic

gradual decline in renal function , often over years

A

chronic kidney disease

40
Q

renail failure - acute or chronic

often medically unwell

A

acute renal failure

41
Q

renail failure - acute or chronic

often multifactorial causes - diabtes, hypertension, atherosclerosis, reflux nephropathy, gn, obstruction of urine outflow

A

chronic kidney disease

42
Q

renail failure - acute or chronic

acute precipitants (drugs, hypovolaemia, sepsis)

A

acute renal failure

43
Q

renail failure - acute or chronic

gradually reducing urine output

A

chronic kidney disease

44
Q

there are many drugs that often exacebate pre-existing renal disease - what particular type of drugs as dentist should we avoid prescribing in renal patients

A

avoid NSAID prescribing in renal patients - paracetamol is analgesic of choice

45
Q

what is glomerulonephritis

A

Glomerulonephritis is damage to the tiny filters inside your kidneys (the glomeruli). It’s often caused by your immune system attacking healthy body tissue.

46
Q

when undergoing dialysis you must make sure that patient is what before you start haemodialysis

A

they are anticoagulated

47
Q

what is An arteriovenous (AV) fistula

A

is an abnormal connection between an artery and a vein in which blood flows directly from an artery into a vein, bypassing some capillaries

48
Q

HLA matching is done before a donor stem cell or organ transplant to find out if tissues match between the donor and the person receiving the transplant.

what is HLA

A

Human Leukocyte Matching

49
Q

can you name the oral manifestations of renal disease

A

xerostomia

taste disturbance

occasional burning sensation of lips and tongue

mucosal pallor - anaemia

renak bone disease: loss of lamina dura, radiolucencies, problems with bone healing post extraction.

50
Q

when would be the best time to perform dental treatment on a patient undergoing dialysis

A

it is best to perform dental treatment day after dialysis

51
Q

what must you never do on the fistual arm

A

do not perform venepuncture or cannulation in fistula arm

52
Q

what would these drugs be used for

prednisolone

azathioprine

cyclosporin

mycophenolate

tacrolimus

A

immuno-suppresants

53
Q

pateints who require dialysis are considered complex patients, who must you consider liaising with renal physicians

A

renal physicians

54
Q

which of these is not a function of the kidney:

salt and water balance

acid base balance

drug excretion

hormone production

glucose homeostasis

A

glucose homeostasis

55
Q

what are the common precipitants in acute kidney injury?

A

acute ilness

sepsis

hypovolaemia

shock haemorrhage

dehydration

56
Q

haemodialysis is performed 3 times per week to replace renal function - true or false

A

true

MWF or TTS

57
Q

chronic kidnet disease results in people often needing lower doses of medication - true or false?

A

true

drug excretion is often impaired in CKD so lower doses of drugs often required.

58
Q
A