Human CNS Development Flashcards

1
Q

What are the primary brain vesicles

A

prosencephalon, mesencephalon and rhombencephalon

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2
Q

What are the secondary brain vesicles

A

diencephalon, metencephalon, telencephalon and myelencephalon

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3
Q

Describe the secondary brain vesicles

A

flexions and out pocketings

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4
Q

Where is white matter located in the spinal cord

A

outside

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5
Q

What is the white matter in the spinal cord

A

myelinated axons

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6
Q

Where is grey matter located in the spinal cord

A

inside

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7
Q

What is the grey matter in the spinal cord

A

soma of neurones

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8
Q

How is matter arranged in the spinal cord

A

opposite to the brain

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9
Q

Where are the cell bodies of afferent fibres located in the spinal cord

A

dorsal root ganglion

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10
Q

What do dorsal roots carry IN to the spinal cord

A

sensory input

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11
Q

What do ventral roots carry OUT of the spinal cord

A

motor commands

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12
Q

What do interneurons connect

A

sensory and motor neurons

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13
Q

What are interneurons important for?

A

stretch reflexes

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14
Q

What reflex doesn’t use interneurons

A

Tendon jerk reflex

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15
Q

Why doesn’t the tendon jerk reflex use interneurons

A

monosynaptic

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16
Q

What are the meninges of the spinal cord

A

pia, arachnoid, and dura

17
Q

Describe the pia mater

A

thin, soft, innermost

18
Q

Describe the arachnoid mater

A

middle, with blood vessels, cobweb look

19
Q

Describe the dura mater

A

tough, double layer

20
Q

What are the two layers of the dura

A

endosteal and meningeal

21
Q

Which layer of the dura is true dura mater and deepest

A

meningeal

22
Q

Where does the CFS flow?

A

central canal, brain ventricles, subarachnoid space

23
Q

What is the function of the CFS

A

float and cushions the CNS

24
Q

What forms the cerebrospinal fluid

A

choroid plexus

25
Q

What absorbs the CFS

A

arachnoid granulations

26
Q

How is the CSF sampled?

A

lumbar puncture between L3 and L4

27
Q

What does CSF composition give information about?

A

state of the CNS

28
Q

Name two disorders of CSF flow

A

hydrocephalus and coning

29
Q

What are the symptoms of hydrocephalus

A

disturbances in fluid, increased intracranial pressure, cell death

30
Q

What are the symptoms of coning?

A

high BP, low HR, loss of brainstem reflexes

31
Q

Describe the BBB

A

semi permeable membrane

32
Q

What does the BBB separate

A

blood from CSF

33
Q

What can pass through the BBB

A

small molecules, fat soluble molecules, some gases

34
Q

What CANNOT pass through the BBB

A

cells, particles, large molecules