Human CNS Development Flashcards

1
Q

What are the primary brain vesicles

A

prosencephalon, mesencephalon and rhombencephalon

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2
Q

What are the secondary brain vesicles

A

diencephalon, metencephalon, telencephalon and myelencephalon

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3
Q

Describe the secondary brain vesicles

A

flexions and out pocketings

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4
Q

Where is white matter located in the spinal cord

A

outside

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5
Q

What is the white matter in the spinal cord

A

myelinated axons

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6
Q

Where is grey matter located in the spinal cord

A

inside

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7
Q

What is the grey matter in the spinal cord

A

soma of neurones

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8
Q

How is matter arranged in the spinal cord

A

opposite to the brain

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9
Q

Where are the cell bodies of afferent fibres located in the spinal cord

A

dorsal root ganglion

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10
Q

What do dorsal roots carry IN to the spinal cord

A

sensory input

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11
Q

What do ventral roots carry OUT of the spinal cord

A

motor commands

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12
Q

What do interneurons connect

A

sensory and motor neurons

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13
Q

What are interneurons important for?

A

stretch reflexes

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14
Q

What reflex doesn’t use interneurons

A

Tendon jerk reflex

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15
Q

Why doesn’t the tendon jerk reflex use interneurons

A

monosynaptic

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16
Q

What are the meninges of the spinal cord

A

pia, arachnoid, and dura

17
Q

Describe the pia mater

A

thin, soft, innermost

18
Q

Describe the arachnoid mater

A

middle, with blood vessels, cobweb look

19
Q

Describe the dura mater

A

tough, double layer

20
Q

What are the two layers of the dura

A

endosteal and meningeal

21
Q

Which layer of the dura is true dura mater and deepest

22
Q

Where does the CFS flow?

A

central canal, brain ventricles, subarachnoid space

23
Q

What is the function of the CFS

A

float and cushions the CNS

24
Q

What forms the cerebrospinal fluid

A

choroid plexus

25
What absorbs the CFS
arachnoid granulations
26
How is the CSF sampled?
lumbar puncture between L3 and L4
27
What does CSF composition give information about?
state of the CNS
28
Name two disorders of CSF flow
hydrocephalus and coning
29
What are the symptoms of hydrocephalus
disturbances in fluid, increased intracranial pressure, cell death
30
What are the symptoms of coning?
high BP, low HR, loss of brainstem reflexes
31
Describe the BBB
semi permeable membrane
32
What does the BBB separate
blood from CSF
33
What can pass through the BBB
small molecules, fat soluble molecules, some gases
34
What CANNOT pass through the BBB
cells, particles, large molecules