Hersh Tb lecture Flashcards
(20 cards)
Weakly G+ rod, branching filaments, aerobic
Nocardia
G+ rod, spore forming, aerobic
Bacillus anthracis
Weakly G+ rod, non-motile, aerobic
mycobacterium tuberculosis
G+ rod, spore forming, anaerobic
Clostridium sp
G+ rod, motile, anaerobic
Listeria monocytogenes
Initial stain to SCREEN for Tb
Auramine-rhodamine stain
Stains to CONFIRM Tb
- Ziehl-Neelsen
- Kinyon
NAAT tests for resistance to what?
Rifampin and INH
add this to 4 drug Tb treatment because of vitamin deficiency
Pyridoxine (B6)
Tb drug that causes eye issues
Ethambutol
Thoracentesis of patient with suspected Tb will contain what
Positive adenosine deaminase
What do you typically see with primary progressive Tb
pleural effusion
Tb virulence factors
- cord factor (release cachectin - wt loss, inhibit phagosome)
- Sulfatides (inhibit phagasome-lysosome fusion)
- Siderophore (Fe2 acquisition)
What does Primary progressive Tb look like
it can lead to miliary Tb and looks like pneumonia
Most common extrapulmonary manifestation of Tb
lymphadenitis . . . SCROFULA
Mycobacerium Kansaii is seen in what kind of patients
-older patients with underlying lung disease or long time smokers in midwest and south west US
Treatment for Mycobacterium Kansaii
Rifampin, Isoniazid, and ethambutol for 18 MONTHS
Lepromin test in tuberculoid leprosy
positive
lepromin test in lepromatous leprosy
negative
Granulomatous lesion of the skin and tendon sheaths after exposure to fish tank or aquarium water
M. marinum
