CMDT pulmonary vascular disease Flashcards

1
Q

Most common inherited cause of PE in white populations

A

resistance to activated protein C, also known as factor V leiden

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2
Q

other risks for hypercoaguability besides factor V leiden

A
  • deficiencies of protein C, S or antithrombin
  • prothrombin gene mutation
  • hyperhomocysteinemia
  • presence of antiphospholipid antibodies (lupus anticoagulant and anticardiolipin antibody)
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3
Q

What radiology is used as the INITIAL diagnostic study for suspected PE?

A

helical CT pulmonary angiography

V/Q scan is also very helpful

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4
Q

What is the reference standard for dianosis of a PE

A

pulmonary angiography

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