Herpes Flashcards

1
Q

Quels sont les traitements des herpes virus et indication

A
HSV/VZV 
- ACICLOVIR iv : 
Hsv : meningoencephalite, 
herpes occulaire grave : keratite, uveite, necrose retine
Gingivostomatite severe
ImmD: primoinf ou reactivations

VZV : encephalite, pneumopathie
ImmoD : varicelle zona

ACICLOVIR Po
Hsv: gingivostomatite herpes severe

VALACICLOVIR PO
Hsv: genital, cutaneomuqux primoinf ou recurrence
Herpes occulaire non severe
Preventif recurrence

VZV : zona ophtalmoque, zona a risque d’algie post zoosterienne
- CMV
ganciclovir iv
Vaganciclovir Po

EBV PAS DE TTT

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2
Q

Traitement gingivostomatite aigue hsv1
Ttt manif occulaire hsv1
Ttt hsv2 genital

A

Valciclovir si tableau marqué
Normalement resolutif en 7-10j

Occulaire : keratite
Aciclovir pommade occu 5x/j x 5-10j
Aciclivir iv keratite profonde, uveite, necrose retine

Genital : valaciclovir 10j primoinf
Valaciclovir5j si recurrence

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3
Q

Quand donner ttt preventif de recurrence herpetique

Quoi

A

> 6 recurrenec/an

Valaciclovir quotidien au long cours

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4
Q

Transmission VZV

A

Plus contagieuse maladie eruptive
CUTANE ET AERIEN TYPE AIR
-2+7 de eruption

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5
Q

Territoire epargne, varicelle

A

Paume main et pied

Et tres presentg cuir chevelu, visage, tronc

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6
Q

Complications de la varicelles

A

1/ surinfection cutane: strepto et staph

Chez immunoD cellulaire, adulte et femme enceinte, NN :
2/ etat inf severe, eruption profise et necrosante, hemorragique
3/ PNEUMONIE INTERTIELLE
4/ neuro : confusion, encephalite, ATAXIE CEREBELLEUSE, polyradiculonevrite, myelite, retinite
5/ PTI aigue

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7
Q

Quand ttt varicelle par antiviral

A

Forme grave extensibe
Forme respiratoire de l’adulte
ImmunoD

ACICLOVIR IV X10j

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8
Q

Indication vaccin VARICELLE

A
Vivant
Ado ou femme age procree ( contraception 1 mois ap inj et bhcg pre vaccin)
Psn non illunise et cintact immunoD
Prof sante petite enfance
>18ans et contact varicelle <3j!!!!!!!
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9
Q

Zona ophtalmique
Quel examen syst
Complication

A

EXAMEN OPHTALMOQUE: risque kératite et iridocyclite ++ si branche nasal externe du trijumeau V1

Paralysie occulomotrice regressive III

DPZ FQQQ INTENSES
SEQUELLE PERTE ANATOMIQUE OEIL
CECITE

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10
Q

Zona gg genicule clinique typique

A

Eruption zone ramsay hunt
PFP
eruption 2/3 hemilangueanterieur homolat
Tb choleovestibulaite

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11
Q

Douleurs post zosterienne

Definition

A

Dlr>1 mois post debut zona ou ap cicatrisation

++++ fq >50 ans, loca cephaliQue, dlr intense phase aigue

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12
Q

Ttt zona

A

Preventif douleur post zosterienne :>50 a, dlr intense , etendu
Tjr si zona ophtalmoque

VALACICLOVIR PO 7j
PRECOCE<72h

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13
Q

Vaccin zona quand

A

Reco 65-74ans

Vivant attenue plus dose que varicelle

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14
Q

Differente forme herpes NN

A

Dissemine polyvisceral av 50% DC
meningo encephalite isole 50% DC
Forle cutaneo muqueuse : guérison 90% cas

Attention si primo onfection <5j acc et + 2j 75% transmission
Ou recurrence 5% transmisso

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