Hepatites Virales Flashcards

1
Q

Quel est le seul virus a etre fait d’ADN?

A

VH B

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2
Q

Quand traiter VHB CHRONIQUE

A

-En fonction de la sévérité, évalué avec :
Transaminases >2
+ replication >2000 ui pcr
+ metavir >A2 ou F2

  • si fibrose extensive >F3
  • si cirrhose
  • ATCD F de CHC et etant vhb+
  • atteinte extra hepatiQue (PAN, glomerulonephrite, cutané)
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3
Q

L’enfant attein de vhb évolue plus vers forme aigue ou chronique

A

95% de forme chronique et d’immuno tolerance <5ans

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4
Q

Phase aigue de vhb repartition des symptomatique et asympto

A

70% asymptomatique
30% symptomatique
1% hepatite fulminante

Puis si >5 ans
10% vont evoluer vers une forme chronique (dont 70% hepatite chrinique et 30% seulement portage inactif) et 90% for.e aigue resolutive

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5
Q

Manif extra bepatique VHC

A
Cryoglobulinemie
Vascularite
Sd sec
Hepatite auto immune
GNMP
porphyrie cut tardive

Loé reaction immune hote

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6
Q

VHB manif extra hep

A

Periarterite noueuse

GNMP

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7
Q

Quels sont les hepatites a DO

A

VhA

VhB

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8
Q

Tableau hepatite aigue : fievre et ictere ou hypertransa

Bilan 1 er i

A

IgM vha

Ag hbs, igM a Hbc

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9
Q

Comment dg+ VHC

A

PAS IGM

IgG a vhc
ARN VHC

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10
Q

Quand suspect vhE

A

Conso porc, voyage endemique tropical
IgM vhE mais + seulement ap min 2 sem
Peu se
Virus ds le plasma ou selles?

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11
Q

Dg HEPATITES VIRALES CHRONIQUES

A

> 6 mois agHBs

>6 m ARN vhc

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12
Q

Quelles sont les hepatites virales qui se chronicise

A

Vhb 5-10%
Vhc 60-70%
Vhd
Vhe ssi immunDq

CIRRHOSE 10-20% vhb vhc chronique
CHC 2-3% et meme si pas cirrhose pour vhb

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13
Q

Quels virus cytopathogene pour foie et peu cytopathogene

A

Vha : non cytopathogene
Vhb : peu cytopathogene
VHC : CYTOPATHOGENE++

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14
Q

Quel est le risque de l’pheoatite virale aigue

A

Surveillance transa, tp, bili/ sem

HEPATITE FULMI AIGIE (ap 2 sem ictere)
Sd hemorragique et encephalopathie hep ( confusion, asterixis, inversion rythme nycthe, somno)

Si TP<50% ou icter prolonge: TRANSPLANTATION HEPATOQUE

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15
Q

Quelle surveillance faire CHC ds hepatite virale chronique

A

Echo abdo/an si cirrhose

/ 2 ans si aghbs + et pas cirrhose

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