Fievre Chez IMMUNOD Flashcards

1
Q
Neutropenie
Baleur
Etio
Site inf
Germes
A

Deficit de immu inne : phagocytose et pce ag
<1500
Etio: leucemie, chimio, radiottt, aplasie med

Bacteries fq du tubes dig, pulm, peau et cathe

BGN : e coli plus fqq
Pseudomonas ae + mortelle!!
Cg+ : staphh
Hsv
Tardif>1 sem : candida et aspergillus
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2
Q

Hypogamma globu
Etio
Bacterie

A
Acquise maladie hemato
Chimio
Sd nephrotique
DICV
congenital

PNQ, HAEMOPHILUS, MENINGOQ

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3
Q

Deficit colplement

A

Diminue activité humoral et opsonisation
Dc bacterie encapsulé
Pnq, hib, meningQ

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4
Q

Deficit immu cellulaire

A

LT : syst adaptatif
Vih, corticott, immS,

Bacteries opportunistes
Listeria, salmonelle, legionelle, mycobacterie, pneumocystose, toxo, herpes

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5
Q

Risque des examens complementaire immD

A

Radio normal
Pas leucocyturie
Pas de pleyocytose LCR

DS NEUTROPENIE

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6
Q

Ex complementaires neutropenie febrile

A
NfsP
Crp
Hemostase : tp, tca, fibrinogene
Creat, uree
Bhc
Hemocs x2 : perif+ central obligatoire
Bu et ecbu
Coproculture
Prelevelent gorge
RT mais manque de sensibilité dc
TDM inj si neutropenie>1 sem
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7
Q

Ttt agranulocytose febrile

A

Aplasie de duree <7 j et sans signe de garvité : ambu et surveillance
AUGMENTIN OU CEFTRIAXONE/CEFITAXIME +/- ciprofoxacine ou aminosides

APLASIE >7j : BLAct large spectre visant PSeudomonas aerginosa
+/- aminoside si gravite
+/- vanco si suspect staph, sarm

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8
Q

Pec si fievre inexpliqué chez un splenectomisé ou asplenique

A

C3G iv en U: ceftriaxone et cefotaxime

Puis vaccin pneumocoque, HIB, meningiq
AtbP peniV pdt 2 ans post splenectomie

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