hereditary syndromes

Question 1

which hereditary cancer syndromes gives a TSG mutation

Answer 1

BRCA1 and 2

Question 2

what hereditary syndrome is most commonly associated with breast, ovarian, prosate, male breast, pancreatic and melanoma cancer

Answer 2

BRCA1 and 2

Question 3

what genes are affected in lynch syndrome

Answer 3

MLH1, MSH2, MSH6, PMS2 and EPCAM

Question 4

what hereditary syndrome is most commonly associated with endometrial, colon and ovarian cancer

Answer 4

lynch syndrome

Question 5

which hereditary cancer syndrome gives a P53 mutation

Answer 5

li frameni

Question 6

which hereditary cancer syndrome gives a PTEN mutation

Answer 6

cowden

Question 7

when is a cancer hereditary

Answer 7

if the first generation is affected and transmission is predisposing

Question 8

when is the cancer familial

Answer 8

if you cannot (yet) find the transmission pathway in the family

Question 9

in which cancer type is CHEK2 often seen in the netherlands

Answer 9

breast cancer

Question 10

what is the most important gene in melanomas

Answer 10

CDKN2A