colorectal cancer Flashcards
1
Q
which CRC is familial without polyps and monogenic
A
lynch syndrome
2
Q
what is the screening procedure for lynch
A
1x per 2 years, from age 25
3
Q
which CRC is familial with polyps and is dominant
A
FAP
4
Q
which CRS is familial with polyps and is recessive
A
MAP
5
Q
what is the screening procedure for FAP
A
1x per 2 years, from age 12
6
Q
what is the screening procedure for MAP
A
1x 2 years from age 18
7
Q
which gene is mutated in MAP
A
MUTYH
8
Q
which gene is mutated in fAP
A
APC
9
Q
explain why a negative MLH1 staining does not have to mean someone has lynch
A
hypermethylation of MLH1 also causes negative staining but does not cause lynch syndrome
