HEMOSTASIS DISEASES Flashcards

1
Q

what are the vitamin K dependent factors?

A

2, 7,9 10, and protein C

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2
Q

what are the three particular types of bleeding tendencies?

A

Vitamin K Deficiency, Hemophilia, Thrombocytopenia (platelet deficiency)

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3
Q

an infection and inflammation in the liver

A

hepatitis

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4
Q

there is a scarring in your liver

A

cirrhosis

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5
Q

Decreased formation of Vitamin K dependent factors

A

vitamin K

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6
Q

decrease of vitamin K causes?

A

excessive bleeding

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7
Q

where is vitamin K continually synthesized?

A

in the intestinal tract by bacteria

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8
Q

a disease where vitamin K deficiency occurs
as a result of poor absorption of fats from the GIT

A

GI disease

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9
Q

One of the most prevalent causes of Vitamin K deficiency-

A

failure of the liver to secrete bile

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10
Q

is injected into surgical patients with liver disease or with obstructed bile ducts

A

Vitamin K

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11
Q

is the presence of stones in the common bile duct or biliary tree

A

Choledocholithiasis

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12
Q

Bleeding disease that occurs almost exclusively in males

A

Hemophilia

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13
Q

a disease where 85% abnormality or deficiency of Factor VIII

A

Hemophilia A or classic hemophilia

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14
Q

a disease where 15% deficiency of Factor IX

A

Hemophilia B

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15
Q

what are the 2 active components of factor VIII?

A

Large component and smaller componenet

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16
Q

what does the large component in factor VIII cause?

A

Von Willebran Disease

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17
Q

one of the two components of factor VIII where it is the deficiency cause hemophilia

A

Smaller component

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18
Q

Presence of very low number of platelets

A

Thrombocytopenia

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19
Q

The patient has a tendency to bleed usually from many
small venules or capillaries that’s why you have small punctate hemorrhages or small purplish blotches, or we call that ________

A

purpura

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20
Q

n the case of patient presenting dark purplish blotches or there is purpura ,so we call that _______

A

Thrombocytopenic purpura

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21
Q

hemophilia occurs in ______ vessels while thrombocytopenia occurs in _________ vessels.

A

Large, small

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22
Q

what do you call where purpura a larger in cases?

A

ecchymosis

23
Q

it is the bleed of usually from many small venules or capillaries

A

small punctuate hemorrages

24
Q

Bleeding will not occur until the number of platelets falls ____________ u/L

A

below 50,000

25
Q

specific Ab have formed and
react against platelets to destroy them.

A

Idiopathic thrombocytopenic

26
Q

abnormal clot that develops in a blood vessel; immobile

A

Thrombus

27
Q

clot that breaks away from its attachment cause the clot to
flow with the blood; mobile

A

Emboli

28
Q

what are the causes of Thromboembolic conditions?

A

Roughened endothelial surface of a vessel and when it flows slowly

29
Q

Immobility of patients confined to bed plus the practice of propping the knees with pillows

A

Femoral Venous Thrombosis

30
Q

Patients confined to bed such as those in the ICU or bed-
ridden patients have the tendency to form ________

A

intravascular clotting

31
Q

heart going to the lungs that would now cause blockage this refers to the condition

A

‘Pulmonary embolism’

32
Q

other term of consumptive coagulopathy

A

disseminated intravascular dissemination

33
Q

Consumption of procoagulants = _____________

A

consumptive coagulopathy

34
Q

what is the quantity of heparin injected in the body?

A

0.5-1 mg/kg

35
Q

how many hours does the heparin last?

A

1.5-4hours

36
Q

what are the active component that fall during warfarin?

A

active prothrombin, Factor VII, IX, and X

37
Q

what are the chemicals used in the prevention of blood coagulation outside the body

A

heparin, oxalate and citrat

38
Q

a prevention of blood coagulation where it is used in surgical procedures in which the blood must be
passed through a heart-lung machine or artificial kidney machine

A

heparin

39
Q

a prevention of blood coagulation where precipitation of calcium oxalate from the plasma and
thereby decreases the ionic calcium level

A

oxalate

40
Q

what is the color of the top of the tube with oxalate?

A

Gray top tube

41
Q

Prevent the initiation of the coagulation system

A

oxalate

42
Q

one of the chemicals for the prevention of blood coagulation where it Prevent the initiation of the coagulation system

A

oxalate

43
Q

lack of clotting factors prolongs?

A

bleeding time

44
Q

a method where you puncture the drop of blood should be
placed in the filter paper and it will be timed. So, the Normal value is 1-6 minutes.

A

IVY METHOD

45
Q

normal time value of clotting in IVY method?

A

1-6 minutes

46
Q

what do you call the time required for coagulation to take place?

A

prothrombin time

47
Q

what is the normal prothrombin time?

A

12 secs

48
Q

puncture the drop of blood should be
placed in the filter paper and it will be timed. So, the Normal value is 1-6 minutes.

A

IVY METHOD

49
Q

INR meaning?

A

international Normalized Ratio

50
Q

what is the normal INR range?, Risk of high bleeding? clotting ratio of INR? of the parathrombin

A

0.9-1.3 , 4-5 , 0.5

51
Q

ndicates the activity of the tissue factor with a standardized sample

A

internal sensitivity index

52
Q

the internal sensitivity index varies between ?

A

1-2

53
Q

normal value of clotting time?

A

6-10 minutes